Anti-Rubella virus E1 antibody [Ru6] (ab82464)

Overview

  • Product nameAnti-Rubella virus E1 antibody [Ru6]
  • Description
    Mouse monoclonal [Ru6] to Rubella virus E1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with Rubella Virus
  • Immunogen

    Purified Rubella virus, strain HPV72.

Properties

Applications

Our Abpromise guarantee covers the use of ab82464 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 52 kDa.
ELISA Use at an assay dependent dilution.

Target

  • RelevanceRubella virus is the only member of the Rubrivirus genus of the Togavirus family. Unlike most Togaviruses it is NOT arthropod borne, but is acquired via the respiratory route. It is an enveloped (toga=cloak), non-segmented, positive sense, RNA virus and replicates in the cytoplasm. It consists of 3 structural proteins; E1,E2 membrane bound glycoproteins, and C capsid protein. E1 envelope glycoprotein is a class II viral fusion protein. Fusion activity is inactive as long as E1 is bound to E2 in mature virion. After virus attachment to target cell and endocytosis, acidification of the endosome induces dissociation of E1/E2 heterodimer and trimerization of the E1 subunits. This E1 homotrimer is fusion active, and promotes release of viral nucleocapsid in the cytoplasm after cell and viral membrane fusion. The E1 cytoplasmic tail modulates virus release, and the tyrosines residues are critical for this function.
  • Alternative names
    • E1 antibody
    • E1 envelope glycoprotein antibody
    • Glycoprotein E1 antibody
    • Spike glycoprotein E1 antibody

References for Anti-Rubella virus E1 antibody [Ru6] (ab82464)

ab82464 has not yet been referenced specifically in any publications.

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Thank you very much for contacting us with your question, and for your patience while I've been in touch with the lab about the epitope of this antibody.
Unfortunately we have not determined the epitope of ab82464. We only know that it binds to t...

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