Anti-RUNX1 / AML1 antibody - ChIP Grade (ab23980)

Publishing research using ab23980? Please let us know so that we can cite the reference in this datasheet.

ab23980 has been referenced in 46 publications.

  • Hu Y  et al. Identification of cardiac hemo-vascular precursors and their requirement of sphingosine-1-phosphate receptor 1 for heart development. Sci Rep 7:45205 (2017). PubMed: 28338096
  • Qin Y  et al. Bone marrow stromal/stem cell-derived extracellular vesicles regulate osteoblast activity and differentiation in vitro and promote bone regeneration in vivo. Sci Rep 6:21961 (2016). PubMed: 26911789
  • Aini H  et al. Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment. Sci Rep 6:18743 (2016). IHC-P ; Mouse . PubMed: 26728350
  • Zang C  et al. NF-E2, FLI1 and RUNX1 collaborate at areas of dynamic chromatin to activate transcription in mature mouse megakaryocytes. Sci Rep 6:30255 (2016). CHIPseq ; Mouse . PubMed: 27457419
  • Unnikrishnan A  et al. A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network. Nucleic Acids Res 44:10644-10661 (2016). WB . PubMed: 27604872
  • Chimge NO  et al. RUNX1 prevents oestrogen-mediated AXIN1 suppression and ß-catenin activation in ER-positive breast cancer. Nat Commun 7:10751 (2016). ChIP . PubMed: 26916619
  • Zheng S  et al. Twist1 and Twist2 Contribute to Cytokine Downregulation following Chronic NOD2 Stimulation of Human Macrophages through the Coordinated Regulation of Transcriptional Repressors and Activators. J Immunol 195:217-26 (2015). ChIP ; Human . PubMed: 26019273
  • Sokol ES  et al. Perturbation-expression analysis identifies RUNX1 as a regulator of human mammary stem cell differentiation. PLoS Comput Biol 11:e1004161 (2015). WB, IHC ; Human . PubMed: 25894653
  • Majumder A  et al. Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1. J Biol Chem 290:13053-63 (2015). PubMed: 25847244
  • Meacham CE  et al. A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth. Genes Dev 29:483-8 (2015). PubMed: 25737277
  • Regha K  et al. Developmental-stage-dependent transcriptional response to leukaemic oncogene expression. Nat Commun 6:7203 (2015). WB ; Mouse . PubMed: 26018585
  • Takayama K  et al. RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer. Oncotarget 6:2263-76 (2015). PubMed: 25537508
  • Ponnusamy K  et al. RUNX1/ETO blocks selectin-mediated adhesion via epigenetic silencing of PSGL-1. Oncogenesis 4:e146 (2015). PubMed: 25867177
  • Kouwenhoven EN  et al. Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation. EMBO Rep 16:863-78 (2015). ChIP . PubMed: 26034101
  • Marks-Bluth J  et al. SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development. Mol Cell Biol 35:2165-72 (2015). PubMed: 25870111
  • Zheng X  et al. Identification of transcription factor AML-1 binding site upstream of human cytomegalovirus UL111A gene. PLoS One 10:e0117773 (2015). ChIP . PubMed: 25658598
  • Ptasinska A  et al. Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal. Cell Rep 8:1974-1988 (2014). ChIP . PubMed: 25242324
  • Wang Y  et al. The transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-?-producing T helper 17 cells. Immunity 40:355-66 (2014). PubMed: 24530058
  • Wang H  et al. NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers. Proc Natl Acad Sci U S A 111:705-10 (2014). ChIP . PubMed: 24374627
  • Bluteau D  et al. Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation. J Clin Invest 124:580-91 (2014). WB, ChIP ; Human . PubMed: 24430186
  • Schmidl C  et al. The enhancer and promoter landscape of human regulatory and conventional T-cell subpopulations. Blood 123:e68-78 (2014). PubMed: 24671953
  • Calero-Nieto FJ  et al. Key regulators control distinct transcriptional programmes in blood progenitor and mast cells. EMBO J 33:1212-26 (2014). CHIPseq ; Mouse . PubMed: 24760698
  • Sashida G  et al. Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation. Nat Commun 5:4177 (2014). PubMed: 24953053
  • Wu M  et al. Deletion of core-binding factor ß (Cbfß) in mesenchymal progenitor cells provides new insights into Cbfß/Runxs complex function in cartilage and bone development. Bone 65:49-59 (2014). PubMed: 24798493
  • Cieslak A  et al. RUNX1-dependent RAG1 deposition instigates human TCR-d locus rearrangement. J Exp Med 211:1821-32 (2014). WB, IP ; Human . PubMed: 25135298
  • Wilkinson AC  et al. RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction. Cell Rep 3:116-27 (2013). IP, CHIPseq ; Human . PubMed: 23352661
  • Kierdorf K  et al. Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways. Nat Neurosci 16:273-80 (2013). Mouse . PubMed: 23334579
  • Wang T  et al. The control of hematopoietic stem cell maintenance, self-renewal, and differentiation by Mysm1-mediated epigenetic regulation. Blood 122:2812-22 (2013). ChIP ; Mouse . PubMed: 24014243
  • Ng KP  et al. Runx1 deficiency permits granulocyte lineage commitment but impairs subsequent maturation. Oncogenesis 2:e78 (2013). ChIP . PubMed: 24189977
  • Lai CB & Mager DL Role of Runt-related Transcription Factor 3 (RUNX3) in Transcription Regulation of Natural Cytotoxicity Receptor 1 (NCR1/NKp46), an Activating Natural Killer (NK) Cell Receptor. J Biol Chem 287:7324-34 (2012). ChIP, EMSA ; Human . PubMed: 22253448
  • Della Gatta G  et al. Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL. Nat Med 18:436-40 (2012). ChIP . PubMed: 22366949
  • Wu JQ  et al. Tcf7 is an important regulator of the switch of self-renewal and differentiation in a multipotential hematopoietic cell line. PLoS Genet 8:e1002565 (2012). PubMed: 22412390
  • Macquarrie KL  et al. miR-206 integrates multiple components of differentiation pathways to control the transition from growth to differentiation in rhabdomyosarcoma cells. Skelet Muscle 2:7 (2012). WB, ChIP . PubMed: 22541669
  • Ptasinska A  et al. Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding. Leukemia 26:1829-41 (2012). ChIP . PubMed: 22343733
  • Scheitz CJ  et al. Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer. EMBO J 31:4124-39 (2012). PubMed: 23034403
  • Soung do Y  et al. Runx1 dose-dependently regulates endochondral ossification during skeletal development and fracture healing. J Bone Miner Res 27:1585-97 (2012). PubMed: 22431360
  • Lichtinger M  et al. RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis. EMBO J 31:4318-33 (2012). ChIP . PubMed: 23064151
  • Giambra V  et al. NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-? and reactive oxygen species. Nat Med 18:1693-8 (2012). ChIP . PubMed: 23086478
  • Paul DS  et al. Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits. PLoS Genet 7:e1002139 (2011). PubMed: 21738486
  • Tijssen MR  et al. Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev Cell 20:597-609 (2011). ChIP . PubMed: 21571218
  • Lazarevic V  et al. T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding ROR?t. Nat Immunol 12:96-104 (2011). WB, IP ; Human . PubMed: 21151104
  • Farrell JJ  et al. A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression. Blood 117:4935-45 (2011). PubMed: 21385855
  • Knezevic K  et al. A Runx1-Smad6 Rheostat Controls Runx1 Activity during Embryonic Hematopoiesis. Mol Cell Biol 31:2817-26 (2011). PubMed: 21576367
  • Wilson NK  et al. Gfi1 expression is controlled by five distinct regulatory regions spread over 100 kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 acting as upstream regulators in early hematopoietic cells. Mol Cell Biol 30:3853-63 (2010). ChIP ; Mouse . PubMed: 20516218
  • Wilson NK  et al. Combinatorial Transcriptional Control In Blood Stem/Progenitor Cells: Genome-wide Analysis of Ten Major Transcriptional Regulators. Cell Stem Cell 7:532-44 (2010). ChIP ; Mouse . PubMed: 20887958
  • Gardini A  et al. AML1/ETO oncoprotein is directed to AML1 binding regions and co-localizes with AML1 and HEB on its targets. PLoS Genet 4:e1000275 (2008). PubMed: 19043539

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