The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesWB: Use at a concentration of 1 - 2 µg/ml. Predicted molecular weight: 96 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceRUSC1 is a putative signaling adapter which may play a role in neuronal differentiation and may be involved in regulation of NGF-dependent neurite outgrowth. It seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK.
Cellular localizationCytoplasm. Nucleus. Note=Translocated to the nuclear envelope upon stimulation with NGF.