Anti-Russells Viper Venom antibody (ab67822)

Overview

  • Product nameAnti-Russells Viper Venom antibody
  • Description
    Duck polyclonal to Russells Viper Venom
  • SpecificityThis antibody specifically recognized russell’s viper venom in western blot analysis; it also partially recognized venom of N. naja atra (45kDa), D. acutus (45 and 105kDa), T.stejnegeri (60 and 105kDa), and T. mucrosquamatus (45 and 105kDa).
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Snake
  • Immunogen

    Snake Venom of Daboia russelli

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.005% Thimerosal (merthiolate)
    Constituents: 0.14M Sodium chloride, 10mM PBS, pH 7.0
  • Concentration information loading...
  • PurityIgY fraction
  • Purification notesThis antibody was purified from egg yolk. Purity was determined by SDS PAGE. IgY(delta Fc) constitutes ~80% of total protein, and the total immunoglobulin IgY+IgY(delta Fc) constitutes ~90% of total protein.
  • ClonalityPolyclonal
  • IsotypeIgY
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab67822 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notesELISA titer : 1/10000
    ELISA titer is defined as the dilution of antibody (1mg/ml) sufficient to give a change in absorbance of 1.0 at 450nm.

    WB: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceDaboia russelli (Russell's viper) is a venomous snake found throughout the Indian subcontinent, much of Southeast Asia, southern China and Taiwan. The venom of this snake is so effective at inducing thrombosis, it has been incorporated into an in vitro diagnostic test for blood clotting that is widely used in hospital laboratories. This test is often referred to as Dilute Russell's viper venom time (dRVVT). The coagulant in the venom directly activates factor X, which turns prothrombin into thrombin in the presence of factor V and phospholipid. The venom is diluted to give a clotting time of 23 to 27 seconds and the phospholipid is reduced to make the test extremely sensitive to phospholipid. The dRVVT test is more sensitive than the aPTT test for the detection of lupus anticoagulant (an autoimmune disorder), because it is not influenced by deficiencies in clotting factors VIII, IX or XI.
    • Cellular localizationSecreted
    • Database links
    • Alternative names
      • Indian Russell's viper venom antibody

    References for Anti-Russells Viper Venom antibody (ab67822)

    ab67822 has not yet been referenced specifically in any publications.

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