Overview

Description

  • NatureSynthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab117773 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-RWDD3 antibody (ab91555)

  • FormLiquid

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.1% BSA

General Info

  • Alternative names
    • DKFZp566K023
    • RSUME
    • RWD containing sumoylation enhancer
    • RWD domain containing 3
    • RWD domain containing protein
    • RWD domain containing protein 3
    • RWD domain-containing protein 3
    • RWD-containing sumoylation enhancer
    • rwdd3
    • RWDD3_HUMAN
    see all
  • FunctionEnhances the sumoylation of a number of proteins including HIF1A, PIAS and I-kappa-B, through direct interaction with UBC9. Has no effect on ubiquitination.
  • Tissue specificityExpressed in a wide number of tissues with highest expression in cerebellum, pituitary, heart, kidney, liver, stomach, pancreas, prostate and spleen. Low levels in thalamus, spinal cord, esophagus, thymus, lung and peripheral blood leukocytes.
  • Sequence similaritiesContains 1 RWD domain.
  • DomainThe RWD domain is required for the sumoylation enhancement activity.
  • Cellular localizationNucleus. Cytoplasm. Colocalizes with UBC9/UBE2I in nuclear spots.
  • Information by UniProt

References for RWDD3 peptide (ab117773)

ab117773 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"