Anti-Ryanodine Receptor 3 antibody - Carboxyterminal end (ab56000)

Overview

  • Product nameAnti-Ryanodine Receptor 3 antibody - Carboxyterminal end
  • Description
    Rabbit polyclonal to Ryanodine Receptor 3 - Carboxyterminal end
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    A synthetic peptide corresponding to C-terminal residues of human Ryanodine Receptor 3

Properties

Applications

Our Abpromise guarantee covers the use of ab56000 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 552 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

Target

  • FunctionCommunication between transverse-tubules and sarcoplasmic reticulum. Contraction of skeletal muscle is triggered by release of calcium ions from SR following depolarization of T-tubules.
  • Tissue specificityBrain, skeletal muscle, placenta and possibly liver and kidney. In brain, highest levels are found in the cerebellum, hippocampus, caudate nucleus and amygdala, with lower levels in the corpus callosum, substantia nigra and thalamus.
  • Sequence similaritiesBelongs to the ryanodine receptor (TC 1.A.3.1) family. RYR3 subfamily.
    Contains 3 B30.2/SPRY domains.
    Contains 1 EF-hand domain.
    Contains 5 MIR domains.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Brain ryanodine receptor calcium release channel antibody
    • Brain ryanodine receptor-calcium release channel antibody
    • Brain type ryanodine receptor antibody
    • Brain-type ryanodine receptor antibody
    • HBRR antibody
    • Ryanodine receptor 3 antibody
    • RYR 3 antibody
    • RYR-3 antibody
    • RyR3 antibody
    • RYR3_HUMAN antibody
    see all

References for Anti-Ryanodine Receptor 3 antibody - Carboxyterminal end (ab56000)

This product has been referenced in:
  • Nensa FM  et al. Amyloid beta a4 precursor protein-binding family B member 1 (FE65) interactomics revealed synaptic vesicle glycoprotein 2A (SV2A) and sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) as new binding proteins in the human brain. Mol Cell Proteomics 13:475-88 (2014). Read more (PubMed: 24284412) »

See 1 Publication for this product

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