Chemical name2-[2-(4-Bromophenyl)-2-oxoethyl]-1-methylpyridinium iodide
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM and in water to 10 mM (with heating)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wang HY et al. Dissociating beta-amyloid from alpha 7 nicotinic acetylcholine receptor by a novel therapeutic agent, S 24795, normalizes alpha 7 nicotinic acetylcholine and NMDA receptor function in Alzheimer's disease brain. J Neurosci29:10961-73 (2009).
Read more (PubMed: 19726654) »
Beracochea D et al. Improvement of contextual memory by S 24795 in aged mice: comparison with memantine. Psychopharmacology (Berl)196:555-64 (2008).
Read more (PubMed: 18034231) »
Lopez-Hernandez G et al. Partial agonist and neuromodulatory activity of S 24795 for alpha7 nAChR responses of hippocampal interneurons. Neuropharmacology53:134-44 (2007).
Read more (PubMed: 17544457) »