Overview

  • Product name
    S-Sulfocysteine sodium salt
  • Description
    Glutamate receptor agonist
  • Biological description
    Glutamate receptor agonist. Glutamate analog. Precursor to L-cysteine. Assumed to cause NMDA receptor-mediated neurodegeneration in molybdenum cofactor deficiency (MoCD) patients. May be involved in cysteine-induced neurotoxicity.

Properties

  • Chemical name
    S-Sulfo-L-cysteine sodium salt
  • Molecular weight
    223.19
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C3H6NNaO5S2
  • CAS Number
    7381-67-1
  • PubChem identifier
    23675751
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    C([C@@H](C(=O)[O-])N)SS(=O)(=O)O.[Na+]
  • Source

    Synthetic

References

This product has been referenced in:
  • Belaidi AA & Schwarz G Molybdenum cofactor deficiency: metabolic link between taurine and S-sulfocysteine. Adv Exp Med Biol 776:13-9 (2013). Read more (PubMed: 23392866) »
  • Nakatani T  et al. Enhancement of thioredoxin/glutaredoxin-mediated L-cysteine synthesis from S-sulfocysteine increases L-cysteine production in Escherichia coli. Microb Cell Fact 11:62 (2012). Read more (PubMed: 22607201) »
  • Abbas AK  et al. S-sulfo-cysteine is an endogenous amino acid in neonatal rat brain but an unlikely mediator of cysteine neurotoxicity. Neurochem Res 33:301-7 (2008). Read more (PubMed: 17764028) »

See 0 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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