Overview

  • Product name
    Anti-S100 alpha antibody [2C8B8]
    See all S100 alpha primary antibodies
  • Description
    Mouse monoclonal [2C8B8] to S100 alpha
  • Tested applications
    Suitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Ni-NTA purified truncated recombinant S100A expressed in E. Coli

  • Positive control
    • Human brain, human lymphoid follicle tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab52271 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 10 kDa.
IHC-P Use at an assay dependent concentration.
ELISA 1/10000.

Target

  • Function
    Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
  • Tissue specificity
    Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.
  • Sequence similarities
    Belongs to the S-100 family.
    Contains 2 EF-hand domains.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Bpb antibody
    • NEF antibody
    • Protein S100-A1 antibody
    • S-100 protein alpha chain antibody
    • S-100 protein subunit alpha antibody
    • S100 alpha antibody
    • S100 Alpha Chain antibody
    • S100 antibody
    • S100 Beta Chain antibody
    • S100 Calcium Binding Protein A1 antibody
    • S100 Calcium Binding Protein B antibody
    • S100 Calcium Binding Protein Beta Neural antibody
    • S100 calcium-binding protein A1 antibody
    • S100 protein alpha polypeptide antibody
    • S100A antibody
    • s100a1 antibody
    • S10A1_HUMAN antibody
    see all

Images

  • All lanes : Anti-S100 alpha antibody [2C8B8] (ab52271)

    Lane 1 : Molecular weight markers
    Lane 2 : Truncated S100A recombinant protein


    Predicted band size : 10 kDa
  • Ab52271 staining human brain tissue; paraffin embedded.
  • Ab52271 staining Human lymphoid follicle tissue; paraffin embedded.

References

ab52271 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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