Overview

  • Product nameAnti-S100 antibody
    See all S100 primary antibodies
  • Description
    Rabbit polyclonal to S100
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant protein encoding human S100 protein.

  • Positive control
    • Melanoma or Schwannoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab15520 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100.

Target

  • FunctionWeakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
  • Tissue specificityHighly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.
  • Sequence similaritiesBelongs to the S-100 family.
    Contains 2 EF-hand domains.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Bpb antibody
    • NEF antibody
    • Protein S100-A1 antibody
    • S-100 protein alpha chain antibody
    • S-100 protein subunit alpha antibody
    • S100 alpha antibody
    • S100 beta antibody
    • S100 calcium binding protein A1 antibody
    • S100 calcium binding protein B antibody
    • S100 calcium-binding protein A1 antibody
    • S100 protein alpha polypeptide antibody
    • S100A antibody
    • s100a1 antibody
    • S100B antibody
    • S100beta antibody
    • S10A1_HUMAN antibody
    see all

Anti-S100 antibody images

  • ab15520 staining S100 at 1/100 dilution in human melanoma by Immunohistochemistry (formalin/paraffin).

References for Anti-S100 antibody (ab15520)

This product has been referenced in:
  • Zhu L  et al. Surgical monotherapy may be a suitable therapeutic strategy for advanced collecting (Bellini) duct carcinoma: A case report and literature review. Exp Ther Med 12:1181-1184 (2016). IHC-P ; Human . Read more (PubMed: 27446340) »
  • Marmotti A  et al. Peroneal tendoscopy. Curr Rev Musculoskelet Med 5:135-44 (2012). IHC-P ; Human . Read more (PubMed: 22527779) »

See all 2 Publications for this product

Product Wall

Thank you for your enquiry. The originator of ab15520 has informed us: "This antibody is raised against S100 beta which is consisted of S100A (S100 alpha and beta) and S100B (2 S100 beta). Therefore this antibody reacts with S100A and S100B subunits." ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"