Anti-S100 antibody [S100 217] (ab115968)

Overview

  • Product nameAnti-S100 antibody [S100 217]
    See all S100 primary antibodies
  • Description
    Mouse monoclonal [S100 217] to S100
  • Tested applicationsSuitable for: IHC-P, IHC-Fr, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Cow, Human, Monkey
  • Immunogen

    Purified Cow S100 protein.

  • Positive control
    • Human Melanoma or schwannoma tissues.
  • General notes


    ab115968 stains schwannoma, ependymomas, astrogliomas, almost all benign and malignant melanoma and their metastases. ab115968 is made with the 22 kDa S100 protein and the antibody reacts with alpha and beta S100 protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab115968 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
IHC-Fr 1/50 - 1/100.
ICC Use at an assay dependent concentration.

Target

  • FunctionWeakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
  • Tissue specificityHighly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.
  • Sequence similaritiesBelongs to the S-100 family.
    Contains 2 EF-hand domains.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Bpb antibody
    • NEF antibody
    • Protein S100-A1 antibody
    • S-100 protein alpha chain antibody
    • S-100 protein subunit alpha antibody
    • S100 alpha antibody
    • S100 beta antibody
    • S100 calcium binding protein A1 antibody
    • S100 calcium binding protein B antibody
    • S100 calcium-binding protein A1 antibody
    • S100 protein alpha polypeptide antibody
    • S100A antibody
    • s100a1 antibody
    • S100B antibody
    • S100beta antibody
    • S10A1_HUMAN antibody
    see all

References for Anti-S100 antibody [S100 217] (ab115968)

ab115968 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry. Yes, both ab7852 and ab115968 react with the alpha and beta subunits of S-100 protein.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"