Overview

  • Product nameAnti-S100 beta antibody [6G1]
    See all S100 beta primary antibodies
  • Description
    Mouse monoclonal [6G1] to S100 beta
  • SpecificityThis antibody is specific for both S100 (beta-beta) and S100 (alpha-beta). Cross reactivity to S100 alpha has not been determined.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified S100 protein from human brain.

Properties

Applications

Our Abpromise guarantee covers the use of ab20327 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
AP
  • Application notesAP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 11 kDa. Dilution optimised using Chromogenic detection. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionWeakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
    • Tissue specificityAlthough predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
    • Sequence similaritiesBelongs to the S-101 family.
      Contains 2 EF-hand domains.
    • Cellular localizationCytoplasm. Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • NEF antibody
      • Protein S100 B antibody
      • Protein S100-B antibody
      • S 100 calcium binding protein beta chain antibody
      • S 100 protein beta chain antibody
      • S-100 protein beta chain antibody
      • S-100 protein subunit beta antibody
      • S100 antibody
      • S100 calcium binding protein beta (neural) antibody
      • S100 calcium-binding protein B antibody
      • S100 protein beta chain antibody
      • S100B antibody
      • S100B_HUMAN antibody
      • S100beta antibody
      see all

    References for Anti-S100 beta antibody [6G1] (ab20327)

    ab20327 has not yet been referenced specifically in any publications.

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