Anti-S100 beta antibody (Biotin) (ab105371)


  • Product nameAnti-S100 beta antibody (Biotin)
    See all S100 beta primary antibodies
  • Description
    Rabbit polyclonal to S100 beta (Biotin)
  • ConjugationBiotin
  • Tested applicationsSuitable for: WB, IP, RIA, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human S100 beta protein purified from Human plasma.



Our Abpromise guarantee covers the use of ab105371 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 11 kDa.
IP Use at an assay dependent concentration.
RIA Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.


  • FunctionWeakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
  • Tissue specificityAlthough predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
  • Sequence similaritiesBelongs to the S-101 family.
    Contains 2 EF-hand domains.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • NEF antibody
    • Protein S100 B antibody
    • Protein S100-B antibody
    • S 100 calcium binding protein beta chain antibody
    • S 100 protein beta chain antibody
    • S-100 protein beta chain antibody
    • S-100 protein subunit beta antibody
    • S100 antibody
    • S100 calcium binding protein beta (neural) antibody
    • S100 calcium-binding protein B antibody
    • S100 protein beta chain antibody
    • S100B antibody
    • S100B_HUMAN antibody
    • S100beta antibody
    see all

References for Anti-S100 beta antibody (Biotin) (ab105371)

ab105371 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Sample Mouse Tissue lysate - whole (HEK and Mouse hippocapus)
Gel Running Conditions Reduced Denaturing (15)
Loading amount 20 µg
Specification HEK and Mouse hippocapus
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C

Abcam user community

Verified customer

Submitted Apr 03 2017

Thank you for contacting us.

I do wish to apologize for the delay in getting this information to you. Ab105371, Anti-S100 beta antibody, is a Biotinylated antibody. The molar ratio is between 2 – 5 biotin molecules per IgG protein. ...

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Thank you for your reply.

My sincere apologies for the confusion. In this case, I am sorry we do not have a suitable standard protein to suggest on this occasion.

In answer to your second question regarding ab48653 and ab105371, I...

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