Anti-S100 beta antibody (Biotin) (ab105371)

Overview

  • Product name
    Anti-S100 beta antibody (Biotin)
    See all S100 beta primary antibodies
  • Description
    Rabbit polyclonal to S100 beta (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: WB, IP, RIA, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human S100 beta protein purified from Human plasma.

Properties

Applications

Our Abpromise guarantee covers the use of ab105371 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 11 kDa.
IP Use at an assay dependent concentration.
RIA Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.

Target

  • Function
    Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
  • Tissue specificity
    Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
  • Sequence similarities
    Belongs to the S-101 family.
    Contains 2 EF-hand domains.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • NEF antibody
    • Protein S100 B antibody
    • Protein S100-B antibody
    • S 100 calcium binding protein beta chain antibody
    • S 100 protein beta chain antibody
    • S-100 protein beta chain antibody
    • S-100 protein subunit beta antibody
    • S100 antibody
    • S100 calcium binding protein beta (neural) antibody
    • S100 calcium-binding protein B antibody
    • S100 protein beta chain antibody
    • S100B antibody
    • S100B_HUMAN antibody
    • S100beta antibody
    see all

References

ab105371 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Western blot
Sample
Mouse Tissue lysate - whole (HEK and Mouse hippocapus)
Gel Running Conditions
Reduced Denaturing (15)
Loading amount
20 µg
Specification
HEK and Mouse hippocapus
Blocking step
BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
Username

Abcam user community

Verified customer

Submitted Apr 03 2017

Thank you for contacting us.

I do wish to apologize for the delay in getting this information to you. Ab105371, Anti-S100 beta antibody, is a Biotinylated antibody. The molar ratio is between 2 – 5 biotin molecules per IgG protein. ...

Read More

Thank you for your reply.

My sincere apologies for the confusion. In this case, I am sorry we do not have a suitable standard protein to suggest on this occasion.

In answer to your second question regarding ab48653 and ab105371, I...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up