Anti-S100 beta antibody [SH-B1], prediluted (ab51899)

Overview

  • Product nameAnti-S100 beta antibody [SH-B1], prediluted
    See all S100 beta primary antibodies
  • Description
    Mouse monoclonal [SH-B1] to S100 beta, prediluted
  • SpecificityReacts with S-100 ß, S-100 A (alpha/beta) and S-100 B (beta/beta). Does not react with S-100 A0 (alpha/alpha), Calmodulin, Parvalbumin and other Ca-binding proteins.
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Rat, Rabbit, Cow, Cat, Human, Pig
  • Immunogen

    Purified S-100 ß protein from bovine brain.

  • Positive control
    • Skin and myelinated nerves

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab51899 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 100 µl working solution / test. Formaldehyde-fixed tissue should be pre-treated with 0.1% pronase. Unmasking methods involving microwave or steam cooking are not recommended.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionWeakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
    • Tissue specificityAlthough predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
    • Sequence similaritiesBelongs to the S-101 family.
      Contains 2 EF-hand domains.
    • Cellular localizationCytoplasm. Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • NEF antibody
      • Protein S100 B antibody
      • Protein S100-B antibody
      • S 100 calcium binding protein beta chain antibody
      • S 100 protein beta chain antibody
      • S-100 protein beta chain antibody
      • S-100 protein subunit beta antibody
      • S100 antibody
      • S100 calcium binding protein beta (neural) antibody
      • S100 calcium-binding protein B antibody
      • S100 protein beta chain antibody
      • S100B antibody
      • S100B_HUMAN antibody
      • S100beta antibody
      see all

    References for Anti-S100 beta antibody [SH-B1], prediluted (ab51899)

    ab51899 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"