Anti-S100 calcium binding protein A14 antibody [5] (ab65860)

Overview

  • Product name
    Anti-S100 calcium binding protein A14 antibody [5]
    See all S100 calcium binding protein A14 primary antibodies
  • Description
    Mouse monoclonal [5] to S100 calcium binding protein A14
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant protein (Human) expressed in E. coli.

  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

Properties

Applications

Our Abpromise guarantee covers the use of ab65860 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

Target

  • Function
    Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
  • Tissue specificity
    Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes.
  • Sequence similarities
    Belongs to the S-100 family.
    Contains 1 EF-hand domain.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • BCMP84 antibody
    • Protein S100-A14 antibody
    • S100 calcium binding protein A14 antibody
    • S100 calcium-binding protein A14 antibody
    • S100a14 antibody
    • S100A15 antibody
    • S10AE_HUMAN antibody
    • S114 antibody
    see all

Images

  • ab65860 staining human stomach cancer tissue.

References

ab65860 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab65860.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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