Anti-S100A12 antibody [19F5] (ab50250)

Overview

• Product nameAnti-S100A12 antibody [19F5]
  See all S100A12 primary antibodies
• Description
  Mouse monoclonal [19F5] to S100A12
• SpecificityThis antibody reacts specifically with the 10kDa human S100A12 protein. In WB the antibody show no cross reactivity with the following S100 protein family: A7, A8, A9 and A10. Other members of this S100 protein family have not been tested.
• Tested applicationsSuitable for: WBmore details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant full length protein (Human)

• Positive control
  • Recombinant protein and on human neutrophils lysate.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• Storage bufferConstituents: 0.75% Glycine, 1.21% Tris, 2% Sucrose
• Concentration information loading...
• PurityProtein A purified
• ClonalityMonoclonal
• Clone number19F5
• IsotypeIgG1
• Light chain typekappa
• Research areas
  • Immunology
  • Innate Immunity
  • Cytokines
  • Other

  • Signal Transduction
  • Signaling Pathway
  • Calcium Signaling
  • Calcium Binding Proteins

  • Immunology
  • Secreted Molecules
  • Other secreted molecules

Associated products

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

Applications

Target

• FunctionCalcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus. Binds calcium, zinc and copper. Presence of zinc increases the affinity for calcium. Plays an important role in the inflammatory response. Interaction with AGER on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators.
• Tissue specificityMonocytes and lymphocytes.
• Sequence similaritiesBelongs to the S-101 family.
  Contains 2 EF-hand domains.

• Target information above from: UniProt accession P80511 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 6283 Human
  • Omim: 603112 Human
  • SwissProt: P80511 Human
  • Unigene: 19413 Human
• Alternative names
  • CAAF1 antibody
  • CAGC antibody
  • Calcitermin antibody

  • Calcium-binding protein in amniotic fluid 1 antibody
  • Calgranulin C antibody
  • Calgranulin-C antibody
  • Calgranulin-related protein antibody
  • CGRP antibody
  • EN RAGE antibody
  • EN-RAGE antibody
  • ENRAGE antibody
  • Extracellular newly identified RAGE-binding protein antibody
  • migration inhibitory factor-related protein 6 antibody
  • MRP6 antibody
  • Neutrophil S100 protein antibody
  • p6 antibody
  • Protein S100 A12 antibody
  • S100 calcium binding protein A12 antibody
  • S100 calcium-binding protein A12 (calgranulin C) antibody
  • S100 calcium-binding protein A12 antibody
  • S100A12 antibody
  • S10AC_HUMAN antibody

  see all