Anti-S100A12 antibody [19F5] (ab50250)

Abreviews (1)Q&A (1)

Overview

  • Product name
    Anti-S100A12 antibody [19F5]
    See all S100A12 primary antibodies
  • Description
    Mouse monoclonal [19F5] to S100A12
  • Host species
    Mouse
  • Specificity
    This antibody reacts specifically with the 10kDa human S100A12 protein. In WB the antibody show no cross reactivity with the following S100 protein family: A7, A8, A9 and A10. Other members of this S100 protein family have not been tested.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human)

  • Positive control
    • Recombinant protein and on human neutrophils lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab50250 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/1000. Predicted molecular weight: 10 kDa.

Target

  • Function
    Calcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus. Binds calcium, zinc and copper. Presence of zinc increases the affinity for calcium. Plays an important role in the inflammatory response. Interaction with AGER on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators.
  • Tissue specificity
    Monocytes and lymphocytes.
  • Sequence similarities
    Belongs to the S-101 family.
    Contains 2 EF-hand domains.
  • Information by UniProt
  • Database links
    • Alternative names
      • CAAF1 antibody
      • CAGC antibody
      • Calcitermin antibody
      • Calcium-binding protein in amniotic fluid 1 antibody
      • Calgranulin C antibody
      • Calgranulin-C antibody
      • Calgranulin-related protein antibody
      • CGRP antibody
      • EN RAGE antibody
      • EN-RAGE antibody
      • ENRAGE antibody
      • Extracellular newly identified RAGE-binding protein antibody
      • migration inhibitory factor-related protein 6 antibody
      • MRP6 antibody
      • Neutrophil S100 protein antibody
      • p6 antibody
      • Protein S100 A12 antibody
      • S100 calcium binding protein A12 antibody
      • S100 calcium-binding protein A12 (calgranulin C) antibody
      • S100 calcium-binding protein A12 antibody
      • S100A12 antibody
      • S10AC_HUMAN antibody
      see all

    References

    ab50250 has not yet been referenced specifically in any publications.

    Publishing research using ab50250? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

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    2 reviews or Q&A

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    Votes: Highest First

    Dear , This customer advanced an enquiry about ab37657 and ab50250. He would like to conduct the non-conventional application, and he wants to know which antibody (ab37657 or ab50250) can be used to pair with the antigen ab103393. Would...

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    Thank you for your reply and for kindly confirming these details. No problem, I wanted to ensure I had the correct information so I could provide an accurate answer for you. I can confirm the following details regarding these products: ab...

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    Western blot abreview for Anti-S100A12 antibody [19F5]

     Below Average
    Abreviews
    Application
    Western blot
    Sample
    Human Tissue lysate - whole (urine)
    Loading amount
    0.6 µg
    Specification
    urine
    Gel Running Conditions
    Reduced Denaturing (18% gel)
    Blocking step
    BSA as blocking agent for 12 hour(s) and 0 minute(s) · Concentration: 1% · Temperature: 4°C
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    Verified customer

    Submitted Jan 10 2011

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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