Anti-S100A12 antibody [19F5] (ab50250)

Overview

  • Product nameAnti-S100A12 antibody [19F5]
    See all S100A12 primary antibodies
  • Description
    Mouse monoclonal [19F5] to S100A12
  • SpecificityThis antibody reacts specifically with the 10kDa human S100A12 protein. In WB the antibody show no cross reactivity with the following S100 protein family: A7, A8, A9 and A10. Other members of this S100 protein family have not been tested.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human)

  • Positive control
    • Recombinant protein and on human neutrophils lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab50250 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/1000. Predicted molecular weight: 10 kDa.

Target

  • FunctionCalcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus. Binds calcium, zinc and copper. Presence of zinc increases the affinity for calcium. Plays an important role in the inflammatory response. Interaction with AGER on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators.
  • Tissue specificityMonocytes and lymphocytes.
  • Sequence similaritiesBelongs to the S-101 family.
    Contains 2 EF-hand domains.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAAF1 antibody
    • CAGC antibody
    • Calcitermin antibody
    • Calcium-binding protein in amniotic fluid 1 antibody
    • Calgranulin C antibody
    • Calgranulin-C antibody
    • Calgranulin-related protein antibody
    • CGRP antibody
    • EN RAGE antibody
    • EN-RAGE antibody
    • ENRAGE antibody
    • Extracellular newly identified RAGE-binding protein antibody
    • migration inhibitory factor-related protein 6 antibody
    • MRP6 antibody
    • Neutrophil S100 protein antibody
    • p6 antibody
    • Protein S100 A12 antibody
    • S100 calcium binding protein A12 antibody
    • S100 calcium-binding protein A12 (calgranulin C) antibody
    • S100 calcium-binding protein A12 antibody
    • S100A12 antibody
    • S10AC_HUMAN antibody
    see all

References for Anti-S100A12 antibody [19F5] (ab50250)

ab50250 has not yet been referenced specifically in any publications.

Product Wall

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Application Western blot
Sample Human Tissue lysate - whole (urine)
Loading amount 0.6 µg
Specification urine
Gel Running Conditions Reduced Denaturing (18% gel)
Blocking step BSA as blocking agent for 12 hour(s) and 0 minute(s) · Concentration: 1% · Temperature: 4°C
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Submitted Jan 10 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"