Overview
- Product nameAnti-sTRAIL Receptor 2 antibodySee all sTRAIL Receptor 2 primary antibodies ...
- DescriptionRabbit polyclonal to sTRAIL Receptor 2
- Tested applicationsWB, Sandwich ELISA more details
- Species reactivityReacts with: Recombinant Fragment
Predicted to work with: Human - Immunogen
Highly pure (>98%) recombinant Human sTRAIL Receptor 2.
- General notesAvoid repeated freeze-thaw cycles.
Properties
- FormLyophilised:Reconstitute in sterile water to a concentration of 1.0 mg/ml. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
- Storage instructionsStore at -20°C, Stable for 6 months at -20°C
- Storage bufferpH: 7.20
Constituent: 99% PBS -
Concentration information loading... - PurityProtein A purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab116627 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 48 kDa. The detection limit for recombinant Human sTRAIL Receptor 2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. |
| Sandwich ELISA | sELISA: Use a concentration of 0.5 - 2 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human sTRAIL Receptor 2. |
Target
- RelevanceTRAIL Receptor 2 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
- Cellular localizationCell Membrane
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Database links
- Entrez Gene: 8795 Human
- Omim: 603612 Human
- SwissProt: O14763 Human
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Alternative names
- Apoptosis inducing protein TRICK2A 2B antibodyApoptosis inducing receptor TRAIL R2 antibodyCD262 antibody
- CD262 antigen antibodyCytotoxic TRAIL receptor 2 antibodyDeath domain containing receptor for TRAIL Apo 2L antibodyDeath receptor 5 antibodyDR5 antibodyFas like protein antibodyKiller antibodyKiller DR5 antibodyp53 regulated DNA damage inducible cell death receptor killer antibodyTNF related apoptosis inducing ligand receptor 2 antibodyTNFRSF10B antibodyTrail R2 antibodyTRAIL receptor 2 antibodyTRAILR2 antibodyTRICK2 antibodyTRICK2A antibodyTRICKB antibodyTumor necrosis factor receptor like protein ZTNFR9 antibodyTumor necrosis factor receptor superfamily member 10B antibodyZTNFR9 antibody
see all
References for Anti-sTRAIL Receptor 2 antibody (ab116627)
ab116627 has not yet been referenced specifically in any publications.
