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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 103 kDa.
1/100 - 1/200.
Function Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. Can inhibit cell proliferation.
Tissue specificity Ubiquitous. Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
Sequence similarities Contains 1 RRM (RNA recognition motif) domain. Contains 1 SAP domain.
Cellular localization Nucleus.
Information by UniProt
glutathione S transferase fusion protein antibody
Anti-SAFB antibody images
Western blot - SAFB antibody (ab97520)
Anti-SAFB antibody (ab97520) at 1/1000 dilution + A431 whole cell lysate at 30 µg Predicted band size : 103 kDa
Immunocytochemistry/ Immunofluorescence - SAFB antibody (ab97520)
ab97520, at a 1/100 dilution, staining SAFB in paraformaldehyde fixed HeLa cells by Immunofluorescence analysis. Lower image was merged with DNA probe.
References for Anti-SAFB antibody (ab97520)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"