Biological descriptionSelective, long acting β2 adrenoceptor agonist. Inhibits release of histamine, leukotrienes, prostaglandin D2 and GM-CSF in concentration-dependent manner. Active in vitro and in vivo.
Chemical name4-Hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol xinafoate
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol to 25 mM and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Fuso L et al. Long-acting beta-agonists and their association with inhaled corticosteroids in COPD. Curr Med Chem20:1477-95 (2013).
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Akabane H et al. Effects of salmeterol xinafoate and fluticasone propionate on immunological activation of human cultured mast cells. Allergol Int55:387-93 (2006).
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Brogden RN & Faulds D Salmeterol xinafoate: a review of its pharmacological properties and therapeutic potential in reversible obstructive airways disease. Allergol Immunopathol (Madr)20:72-84 (0).
Read more (PubMed: 1359777) »