Overview

  • Product name
  • Description
    Rabbit polyclonal to SAMSN1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide corresponding to a region within internal sequence amino acids 262-291 of Human SAMSN1 (NP_071419.3).

  • Positive control
    • Jurkat cell line lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab107438 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab107438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 42 kDa.

Target

  • Function
    Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation.
  • Tissue specificity
    Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood.
  • Sequence similarities
    Contains 1 SAM (sterile alpha motif) domain.
    Contains 1 SH3 domain.
  • Cellular localization
    Nucleus. Cytoplasm. Cell projection > ruffle. Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles.
  • Information by UniProt
  • Database links
  • Alternative names
    • HACS1 antibody
    • Hematopoietic adapter containing SH3 and sterile α motif (SAM) domains 1 antibody
    • Hematopoietic adapter containing SH3 and sterile alpha motif (SAM) domains 1 antibody
    • Hematopoietic adaptor containing SH3 and SAM domains 1 antibody
    • Nash1 antibody
    • Nuclear localization signals SAM and SH3 domain containing 1 antibody
    • SAM and SH3 domain containing 2 antibody
    • SAM domain antibody
    • SAM domain containing protein SAMSN 1 antibody
    • SAM domain SH3 domain and nuclear localisation signals 1 antibody
    • SAM domain SH3 domain and nuclear localization signals 1 antibody
    • SAM domain, SH3 domain and nuclear localization signals protein 1 antibody
    • SAM domain-containing protein SAMSN-1 antibody
    • SAMN1_HUMAN antibody
    • SAMSN 1 antibody
    • Samsn1 antibody
    • SASH2 antibody
    • SH3 domain and nuclear localisation signals 1 antibody
    • SH3 domain and nuclear localization signals protein 1 antibody
    • SH3 SAM adaptor protein antibody
    • SH3-SAM adaptor protein antibody
    • SH3D6B antibody
    • SLy2 antibody
    • Src homology domain 3 (SH3) containing adapter protein SH3 lymphocyte protein 2 antibody
    see all

Images

  • Anti-SAMSN1 antibody (ab107438) at 1/100 dilution + Jurkat cell line lysate at 35 µg

    Predicted band size : 42 kDa

References

ab107438 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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