Overview

  • Product nameAnti-SAMSN1 antibody
    See all SAMSN1 primary antibodies
  • Description
    Mouse monoclonal to SAMSN1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-374 of Human SAMSN1

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab56360 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionNegative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation.
    • Tissue specificityDetected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood.
    • Sequence similaritiesContains 1 SAM (sterile alpha motif) domain.
      Contains 1 SH3 domain.
    • Cellular localizationNucleus. Cytoplasm. Cell projection > ruffle. Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles.
    • Information by UniProt
    • Database links
    • Alternative names
      • HACS1 antibody
      • Hematopoietic adapter containing SH3 and sterile α motif (SAM) domains 1 antibody
      • Hematopoietic adapter containing SH3 and sterile alpha motif (SAM) domains 1 antibody
      • Hematopoietic adaptor containing SH3 and SAM domains 1 antibody
      • Nash1 antibody
      • Nuclear localization signals SAM and SH3 domain containing 1 antibody
      • SAM and SH3 domain containing 2 antibody
      • SAM domain antibody
      • SAM domain containing protein SAMSN 1 antibody
      • SAM domain SH3 domain and nuclear localisation signals 1 antibody
      • SAM domain SH3 domain and nuclear localization signals 1 antibody
      • SAM domain, SH3 domain and nuclear localization signals protein 1 antibody
      • SAM domain-containing protein SAMSN-1 antibody
      • SAMN1_HUMAN antibody
      • SAMSN 1 antibody
      • Samsn1 antibody
      • SASH2 antibody
      • SH3 domain and nuclear localisation signals 1 antibody
      • SH3 domain and nuclear localization signals protein 1 antibody
      • SH3 SAM adaptor protein antibody
      • SH3-SAM adaptor protein antibody
      • SH3D6B antibody
      • SLy2 antibody
      • Src homology domain 3 (SH3) containing adapter protein SH3 lymphocyte protein 2 antibody
      see all

    Anti-SAMSN1 antibody images

    • Western blot against tagged recombinant protein immunogen using ab56360 SAMSN1 antibody at 1ug/ml. Predicted band size of immunogen is 67 kDa

    References for Anti-SAMSN1 antibody (ab56360)

    ab56360 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab56360.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"