Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab5841 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-SAP102 antibody (ab3438)

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • bA291O7.3
    • bA291O7.3 discs large Drosophila homolog 3 neuroendocrine dlg
    • Discs large Drosophila homolog 3
    • Discs large homolog 3
    • Discs large homolog 3 neuroendocrine dlg Drosophila
    • Discs large homolog 3 Drosophila
    • Discs, large homolog 3 (Drosophila)
    • Disks large homolog 3
    • DLG 3
    • Dlg3
    • DLG3_HUMAN
    • KIAA1232
    • mKIAA1232
    • MRX
    • MRX 90
    • MRX90
    • NE Dlg
    • NEDLG
    • Neuroendocrine dlg
    • Neuroendocrine-DLG
    • OTTHUMP00000023475
    • OTTHUMP00000023476
    • OTTHUMP00000023477
    • SAP 102
    • SAP-102
    • SAP102
    • Synapse associated protein 102
    • Synapse-associated protein 102
    • XLMR
    see all
  • Function
    Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.
  • Involvement in disease
    Defects in DLG3 are the cause of mental retardation X-linked type 90 (MRX90) [MIM:300189]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
  • Sequence similarities
    Belongs to the MAGUK family.
    Contains 1 guanylate kinase-like domain.
    Contains 3 PDZ (DHR) domains.
    Contains 1 SH3 domain.
  • Information by UniProt

References

ab5841 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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