Anti-Sarcomeric Alpha Actinin antibody [EA-53] (ab9465)

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ab9465 has been referenced in 62 publications.

  • Nixon BR  et al. Alterations in sarcomere function modify the hyperplastic to hypertrophic transition phase of mammalian cardiomyocyte development. JCI Insight 2:e90656 (2017). PubMed: 28239655
  • Palazzolo G  et al. Cardiac Niche Influences the Direct Reprogramming of Canine Fibroblasts into Cardiomyocyte-Like Cells. Stem Cells Int 2016:4969430 (2016). PubMed: 26681949
  • Loperfido M  et al. piggyBac transposons expressing full-length human dystrophin enable genetic correction of dystrophic mesoangioblasts. Nucleic Acids Res 44:744-60 (2016). IF . PubMed: 26682797
  • Quinn TA  et al. Electrotonic coupling of excitable and nonexcitable cells in the heart revealed by optogenetics. Proc Natl Acad Sci U S A 113:14852-14857 (2016). PubMed: 27930302
  • Kanazawa H  et al. Durable Benefits of Cellular Postconditioning: Long-Term Effects of Allogeneic Cardiosphere-Derived Cells Infused After Reperfusion in Pigs with Acute Myocardial Infarction. J Am Heart Assoc 5:N/A (2016). IHC-P ; Pig . PubMed: 26857066
  • Chiou KK  et al. Mechanical signaling coordinates the embryonic heartbeat. Proc Natl Acad Sci U S A 113:8939-44 (2016). PubMed: 27457951
  • Hansen KJ  et al. Functional Effects of Delivering Human Mesenchymal Stem Cell-Seeded Biological Sutures to an Infarcted Heart. Biores Open Access 5:249-60 (2016). IHC ; Rat . PubMed: 27610271
  • Nandi SS  et al. Lack of miR-133a Decreases Contractility of Diabetic Hearts: A Role for Novel Cross Talk Between Tyrosine Aminotransferase and Tyrosine Hydroxylase. Diabetes 65:3075-90 (2016). PubMed: 27411382
  • Biswas H & Longmore GD Action of SNAIL1 in Cardiac Myofibroblasts Is Important for Cardiac Fibrosis following Hypoxic Injury. PLoS One 11:e0162636 (2016). Mouse . PubMed: 27706205
  • Smith SJ  et al. The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly. Dev Biol 416:373-88 (2016). PubMed: 27217161
  • Maillet A  et al. Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes. Sci Rep 6:25333 (2016). ICC/IF ; Human . PubMed: 27142468
  • Broughton KM  et al. A myosin activator improves actin assembly and sarcomere function of human-induced pluripotent stem cell-derived cardiomyocytes with a troponin T point mutation. Am J Physiol Heart Circ Physiol 311:H107-17 (2016). IHC (PFA fixed) ; Rat . PubMed: 27199119
  • Okamoto-Uchida Y  et al. The mevalonate pathway regulates primitive streak formation via protein farnesylation. Sci Rep 6:37697 (2016). WB ; Human . PubMed: 27883036
  • Greco CM  et al. DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy. Nat Commun 7:12418 (2016). Flow Cyt . PubMed: 27489048
  • Fan X  et al. Matrix metalloproteinase-2 in oncostatin M-induced sarcomere degeneration in cardiomyocytes. Am J Physiol Heart Circ Physiol 311:H183-9 (2016). Rat . PubMed: 27199120
  • He Q  et al. Lycopene attenuates inflammation and apoptosis in post-myocardial infarction remodeling by inhibiting the nuclear factor-?B signaling pathway. Mol Med Rep 11:374-8 (2015). IHC-P ; Mouse . PubMed: 25323011
  • Kanazawa H  et al. Cellular postconditioning: allogeneic cardiosphere-derived cells reduce infarct size and attenuate microvascular obstruction when administered after reperfusion in pigs with acute myocardial infarction. Circ Heart Fail 8:322-32 (2015). IHC-P ; Pig . PubMed: 25587096
  • Anekal PV  et al. Arg kinase-binding protein 2 (ArgBP2) interaction with a-actinin and actin stress fibers inhibits cell migration. J Biol Chem 290:2112-25 (2015). PubMed: 25429109
  • Fan X  et al. Dynamic Alterations to a-Actinin Accompanying Sarcomere Disassembly and Reassembly during Cardiomyocyte Mitosis. PLoS One 10:e0129176 (2015). ICC/IF ; Rat . PubMed: 26076379
  • Suhaeri M  et al. Cardiomyoblast (h9c2) differentiation on tunable extracellular matrix microenvironment. Tissue Eng Part A 21:1940-51 (2015). PubMed: 25836924
  • Lin YH  et al. Cyclic mechanical strain of myocytes modifies CapZß1 post translationally via PKCe. J Muscle Res Cell Motil 36:329-37 (2015). PubMed: 26429793
  • Zhang B  et al. Platform technology for scalable assembly of instantaneously functional mosaic tissues. Sci Adv 1:e1500423 (2015). IF . PubMed: 26601234
  • Broughton KM & Russell B Cardiomyocyte subdomain contractility arising from microenvironmental stiffness and topography. Biomech Model Mechanobiol 14:589-602 (2015). ICC/IF ; Rat . PubMed: 25273278
  • Kuang J  et al. Myocardial apoptosis and injury of donor hearts kept in completely beating status with normothermic blood perfusion for transplants. Int J Clin Exp Med 8:5767-73 (2015). PubMed: 26131163
  • Asiri AM  et al. Understanding greater cardiomyocyte functions on aligned compared to random carbon nanofibers in PLGA. Int J Nanomedicine 10:89-96 (2015). PubMed: 25565806
  • Mueller JL  et al. Functional consequences of EpCam mutation in mice and men. Am J Physiol Gastrointest Liver Physiol 306:G278-88 (2014). PubMed: 24337010
  • Strakova J  et al. Dystrobrevin increases dystrophin's binding to the dystrophin-glycoprotein complex and provides protection during cardiac stress. J Mol Cell Cardiol 76:106-15 (2014). PubMed: 25158611
  • Mei JC  et al. Three-dimensional extracellular matrix scaffolds by microfluidic fabrication for long-term spontaneously contracted cardiomyocyte culture. Tissue Eng Part A 20:2931-41 (2014). PubMed: 24851797
  • Liu Z  et al. Essential role of the zinc finger transcription factor Casz1 for mammalian cardiac morphogenesis and development. J Biol Chem 289:29801-16 (2014). IHC ; Mouse . PubMed: 25190801
  • Li J  et al. Actin dynamics is rapidly regulated by the PTEN and PIP2 signaling pathways leading to myocyte hypertrophy. Am J Physiol Heart Circ Physiol 307:H1618-25 (2014). PubMed: 25260617
  • Svensson Holm AC  et al. Thyroid hormone does not induce maturation of embryonic chicken cardiomyocytes in vitro. Physiol Rep 2:N/A (2014). PubMed: 25501434
  • Lichter JG  et al. Remodeling of the sarcomeric cytoskeleton in cardiac ventricular myocytes during heart failure and after cardiac resynchronization therapy. J Mol Cell Cardiol 72:186-95 (2014). PubMed: 24657727
  • Salick MR  et al. Micropattern width dependent sarcomere development in human ESC-derived cardiomyocytes. Biomaterials N/A:N/A (2014). PubMed: 24582552
  • Becker JR  et al. Differential activation of natriuretic peptide receptors modulates cardiomyocyte proliferation during development. Development 141:335-45 (2014). PubMed: 24353062
  • Rouède D  et al. Myofibrillar misalignment correlated to triad disappearance of mdx mouse gastrocnemius muscle probed by SHG microscopy. Biomed Opt Express 5:858-75 (2014). IF ; Mouse . PubMed: 24688819
  • Ren Y  et al. Potential of adipose-derived mesenchymal stem cells and skeletal muscle-derived satellite cells for somatic cell nuclear transfer mediated transgenesis in Arbas Cashmere goats. PLoS One 9:e93583 (2014). ICC/IF ; Goat . PubMed: 24699686
  • Zangrando J  et al. Identification of candidate long non-coding RNAs in response to myocardial infarction. BMC Genomics 15:460 (2014). IHC-P ; Mouse . PubMed: 24917243
  • Hu YF  et al. Biological pacemaker created by minimally invasive somatic reprogramming in pigs with complete heart block. Sci Transl Med 6:245ra94 (2014). Pig . PubMed: 25031269
  • Zamperone A  et al. Isolation and characterization of a spontaneously immortalized multipotent mesenchymal cell line derived from mouse subcutaneous adipose tissue. Stem Cells Dev 22:2873-84 (2013). Mouse . PubMed: 23777308
  • Chakraborty S  et al. A robust strategy for negative selection of Cre-loxP recombination-based excision of transgenes in induced pluripotent stem cells. PLoS One 8:e64342 (2013). ICC/IF ; Mouse . PubMed: 23717601
  • Nunes SS  et al. Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes. Nat Methods 10:781-7 (2013). PubMed: 23793239
  • Blömer N  et al. 5-Lipoxygenase facilitates healing after myocardial infarction. Basic Res Cardiol 108:367 (2013). IHC-P . PubMed: 23812248
  • Quattrocelli M  et al. Long-term miR-669a therapy alleviates chronic dilated cardiomyopathy in dystrophic mice. J Am Heart Assoc 2:e000284 (2013). PubMed: 23963759
  • Huang C  et al. Identification of nodal tissue in the living heart using rapid scanning fiber-optics confocal microscopy and extracellular fluorophores. Circ Cardiovasc Imaging 6:739-46 (2013). ICC/IF ; Rat . PubMed: 23811748
  • Bitto FF  et al. Myogenic Differentiation of Mesenchymal Stem Cells in a Newly Developed Neurotised AV-Loop Model. Biomed Res Int 2013:935046 (2013). PubMed: 24106724
  • Carberry S  et al. Comparative proteomic profiling of soleus, extensor digitorum longus, flexor digitorum brevis and interosseus muscles from the mdx mouse model of Duchenne muscular dystrophy. Int J Mol Med 32:544-56 (2013). PubMed: 23828267
  • Curtis MW  et al. Microdomain heterogeneity in 3D affects the mechanics of neonatal cardiac myocyte contraction. Biomech Model Mechanobiol 12:95-109 (2013). ICC/IF . PubMed: 22407215
  • Chow MZ  et al. Epigenetic regulation of the electrophysiological phenotype of human embryonic stem cell-derived ventricular cardiomyocytes: insights for driven maturation and hypertrophic growth. Stem Cells Dev 22:2678-90 (2013). PubMed: 23656529
  • Lasher RA  et al. Electrical stimulation directs engineered cardiac tissue to an age-matched native phenotype. J Tissue Eng 3:2041731412455354 (2012). PubMed: 22919458
  • Ma J  et al. High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents. Am J Physiol Heart Circ Physiol 301:H2006-17 (2011). PubMed: 21890694
  • Burridge PW  et al. A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability. PLoS One 6:e18293 (2011). ICC/IF ; Human . PubMed: 21494607
  • Asumda FZ & Chase PB Age-related changes in rat bone-marrow mesenchymal stem cell plasticity. BMC Cell Biol 12:44 (2011). PubMed: 21992089
  • Geach TJ & Zimmerman LB Paralysis and delayed Z-disc formation in the Xenopus tropicalis unc45b mutant dicky ticker. BMC Dev Biol 10:75 (2010). ICC/IF ; Xenopus tropicalis . PubMed: 20637071
  • Boyer JG  et al. Hearts of Dystonia musculorum mice display normal morphological and histological features but show signs of cardiac stress. PLoS One 5:e9465 (2010). IHC-Fr ; Mouse . PubMed: 20209123
  • Zentilin L  et al. Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction. FASEB J 24:1467-78 (2010). IHC-FoFr ; Rat . PubMed: 20019242
  • Liao IC & Leong KW Efficacy of engineered FVIII-producing skeletal muscle enhanced by growth factor-releasing co-axial electrospun fibers. Biomaterials : (2010). IHC-P ; Mouse . PubMed: 21084118
  • Curtis MW  et al. Hypertrophy, gene expression, and beating of neonatal cardiac myocytes are affected by microdomain heterogeneity in 3D. Biomed Microdevices 12:1073-85 (2010). ICC/IF ; Rat . PubMed: 20668947
  • Pointon AV  et al. Doxorubicin in vivo rapidly alters expression and translation of myocardial electron transport chain genes, leads to ATP loss and caspase 3 activation. PLoS One 5:e12733 (2010). PubMed: 20856801
  • Boateng SY  et al. Myocyte remodeling in response to hypertrophic stimuli requires nucleocytoplasmic shuttling of muscle LIM protein. J Mol Cell Cardiol 47:426-35 (2009). WB ; Rat . PubMed: 19376126
  • Recher G  et al. Three distinct sarcomeric patterns of skeletal muscle revealed by SHG and TPEF microscopy. Opt Express 17:19763-77 (2009). IHC-Fr ; Xenopus laevis . PubMed: 19997197
  • Wu KH  et al. Therapeutic potential of human umbilical cord derived stem cells in a rat myocardial infarction model. Ann Thorac Surg 83:1491-8 (2007). PubMed: 17383364
  • Kucia M  et al. A population of very small embryonic-like (VSEL) CXCR4(+)SSEA-1(+)Oct-4+ stem cells identified in adult bone marrow. Leukemia 20:857-69 (2006). PubMed: 16498386

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