Overview

  • Product nameAnti-SART1 antibody
    See all SART1 primary antibodies
  • Description
    Rabbit polyclonal to SART1
  • Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 137 - 417 of Human SART1

  • Positive control
    • A431,H1299, MOLT4 and Raji cells. Cal27 xenograft.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab95957 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 90 kDa.
IHC-P 1/100 - 1/500.
ICC/IF 1/100 - 1/200.

Target

  • RelevanceSART1 encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri snRNP to the pre spliceosome in the spliceosome assembly pathway.
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • Ara 1 antibody
    • ARA1 antibody
    • HOMS 1 antibody
    • HOMS1 antibody
    • hSART 1 antibody
    • hSART1 antibody
    • hSnu 66 antibody
    • hSnu66 antibody
    • IgE autoantigen antibody
    • MGC2038 antibody
    • SART 1 antibody
    • SART1 259 antibody
    • SART1(259) protein antibody
    • SART1(800) protein antibody
    • SART1259 antibody
    • Snu 66 antibody
    • Snu66 antibody
    • Squamous cell carcinoma antigen recognised by T cells antibody
    • Squamous cell carcinoma antigen recognized by T cells 1 antibody
    • U4/U6.U5 tri snRNP associated 110 kDa protein antibody
    • U4/U6.U5 tri snRNP associated protein 1 antibody
    see all

Anti-SART1 antibody images

  • Anti-SART1 antibody (ab95957) at 1/5000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 90 kDa
  • ab95957, at a 1/200 dilution, staining SART1 in paraformaldehyde fixed A431 by Immunofluorescence.
    Image on the right: merged with DNA probe.
  • ab95957, at a 1/500 dilution, staining SART1 in paraffin embedded Cal27 xenograft by Immunohistochemical analysis.

References for Anti-SART1 antibody (ab95957)

ab95957 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"