Overview

  • Product name
    SB 203580
  • Description
    p38 MAPK inhibitor
  • Biological description
    Cell-permeable p38 MAPK inhibitor. Shows selectivity over many other kinases but also shown to have some inhibitory activity against GAK, CK1, RIP2, c-Raf and GSK3.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Cuenda A & Rousseau S p38 MAP-kinases pathway regulation, function and role in human diseases. Biochim Biophys Acta 1773:1358-75 (2007). Read more (PubMed: 17481747) »
  • Bain J  et al. The selectivity of protein kinase inhibitors: a further update. Biochem J 408:297-315 (2007). Read more (PubMed: 17850214) »
  • Kumar S  et al. Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase. Biochem Biophys Res Commun 263:825-31 (1999). Read more (PubMed: 10512765) »

See all 8 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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