Overview

  • Product nameSB 206553 hydrochloride
  • Description
    Potent, selective 5-HT2B and 5-HT2C receptor agonist
  • Biological descriptionPotent and selective 5-HT2B and 5-HT2C serotonin receptor agonist (pKi values are 7.92 (5-HT2C), 5.78 (5-HT2A), 7.65 (5-HT2B), <5 (5-HT1A), <6 (5-HT1D), <5.3 (5-HT1E) and <5.3 (5-HT1F). Centrally active following oral administration.
  • Purity> 99%

Properties

    References for SB 206553 hydrochloride (ab120556)

    This product has been referenced in:
    • Knight AR  et al. Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. Naunyn Schmiedebergs Arch Pharmacol 370:114-23 (2004). Read more (PubMed: 15322733) »
    • Kennett GA  et al. In vitro and in vivo profile of SB 206553, a potent 5-HT2C/5-HT2B receptor antagonist with anxiolytic-like properties. Br J Pharmacol 117:427-434 (1996). Read more (PubMed: 8821530) »

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