Overview

  • Product name
    SB 216641 hydrochloride
  • Description
    Selective h5-HT1B antagonist
  • Biological description
    Selective h5-HT1B receptor antagonist. 25-fold selectivity over h5-HT1D. Little or no affinity for a range of other receptor subtypes.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Simansky KJ & Nicklous DM Parabrachial infusion of D-fenfluramine reduces food intake. Blockade by the 5-HT(1B) antagonist SB-216641. Pharmacol Biochem Behav 71:681-90 (2002). Read more (PubMed: 11888559) »
  • Price GW  et al. SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors. Naunyn Schmiedebergs Arch Pharmacol 356:312-20 (1997). Read more (PubMed: 9303567) »
  • Schlicker E  et al. Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands on guinea-pig and human 5-HT auto- and heteroreceptors. Naunyn Schmiedebergs Arch Pharmacol 356:321-7 (1997). Read more (PubMed: 9303568) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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