Overview

  • Product name
    Anti-SBEM antibody
  • Description
    Rabbit polyclonal to SBEM
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence AQNPTTAAPA DTYPATGPAD DEAPDAETTA AATTA, corresponding to amino acids 19-53 of Human SBEM (UniProt ID: Q96DR8).

  • Positive control
    • Human breast tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab122530 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May play a role as marker for the diagnosis of metastatic breast cancer.
  • Tissue specificity
    Expressed in mammary, salivary glands and prostate. Also detected in lung. Mainly expressed in cancer cell lines of breast origin. Highly expressed in lymph node-positive compared with node-negative tumors. Detected in all lymph node containing metastatic cells.
  • Post-translational
    modifications
    O-glycosylated.
  • Cellular localization
    Secreted. Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • mucin like 1 antibody
    • mucin-like 1 antibody
    • Mucin-like protein 1 antibody
    • MUCL1 antibody
    • MUCL1_HUMAN antibody
    • Protein BS106 antibody
    • Small breast epithelial mucin antibody
    see all

Images

  • Immunohistochemical staining of SBEM in paraffin embedded Human breast tissue by Immunohistochemistry, using ab122530 at a 1/20 dilution. The image shows moderate cytoplasmic and extracellular positivity in glandular cells.

References

This product has been referenced in:
  • Liu L  et al. Small breast epithelial mucin tumor tissue expression is associated with increased risk of recurrence and death in triple-negative breast cancer patients. Diagn Pathol 8:71 (2013). Histology ; Human . Read more (PubMed: 23635316) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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