Overview

  • Product name
    SC-66
  • Description
    Allosteric Akt inhibitor
  • Biological description
    Allosteric Akt inhibitor. Interferes with PIP3 binding to Akt's PH domain. Additionally facilitates Akt ubiquitination. Displays anticancer activity in vitro and in vivo.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Jo H  et al. Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination. Proc Natl Acad Sci U S A 108:6486-91 (2011). Read more (PubMed: 21464312) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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