Anti-SC35 antibody [SC-35] - Nuclear Speckle Marker (ab11826)

Publishing research using ab11826? Please let us know so that we can cite the reference in this datasheet.

ab11826 has been referenced in 44 publications.

  • Deane CAS & Brown IR Differential Targeting of Hsp70 Heat Shock Proteins HSPA6 and HSPA1A with Components of a Protein Disaggregation/Refolding Machine in Differentiated Human Neuronal Cells following Thermal Stress. Front Neurosci 11:227 (2017). ICC/IF ; Human . PubMed: 28484369
  • Stopford MJ  et al. C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten. Hum Mol Genet 26:1133-1145 (2017). ICC/IF ; Mouse . PubMed: 28158451
  • Homma S  et al. Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4. Skelet Muscle 6:42 (2016). ICC/IF ; Human . PubMed: 27906075
  • Anderson DM  et al. Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106. Proc Natl Acad Sci U S A 113:E4494-503 (2016). IHC-P . PubMed: 27418600
  • Skrdlant L  et al. Myelodysplasia-associated mutations in serine/arginine-rich splicing factor SRSF2 lead to alternative splicing of CDC25C. BMC Mol Biol 17:18 (2016). ICC/IF ; Human . PubMed: 27552991
  • Taylor SE  et al. Differential sub-nuclear distribution of hypoxia-inducible factors (HIF)-1 and -2 alpha impacts on their stability and mobility. Open Biol 6:N/A (2016). ICC/IF ; Human . PubMed: 27655733
  • Lin Y  et al. Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers. Cell 167:789-802.e12 (2016). Human . PubMed: 27768897
  • McCuaig RD  et al. PKC-Theta is a Novel SC35 Splicing Factor Regulator in Response to T Cell Activation. Front Immunol 6:562 (2015). ICC/IF ; Human . PubMed: 26594212
  • Carmona-Mora P  et al. The nuclear localization pattern and interaction partners of GTF2IRD1 demonstrate a role in chromatin regulation. Hum Genet N/A:N/A (2015). ICC/IF . PubMed: 26275350
  • Vega SL  et al. Organizational metrics of interchromatin speckle factor domains: integrative classifier for stem cell adhesion & lineage signaling. Integr Biol (Camb) 7:435-46 (2015). ICC/IF ; Human . PubMed: 25765854
  • Pawellek A  et al. Identification of small molecule inhibitors of pre-mRNA splicing. J Biol Chem 289:34683-98 (2014). ICC/IF ; Human . PubMed: 25281741
  • Udan-Johns M  et al. Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones. Hum Mol Genet 23:157-70 (2014). PubMed: 23962724
  • Park R  et al. Nuclear translocation and regulation of intranuclear distribution of cytoplasmic poly(A)-binding protein are distinct processes mediated by two Epstein Barr virus proteins. PLoS One 9:e92593 (2014). ICC/IF ; Human . PubMed: 24705134
  • Cooper-Knock J  et al. Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions. Brain 137:2040-51 (2014). IHC-P ; Human . PubMed: 24866055
  • Ammon T  et al. The conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells. J Mol Cell Biol 6:312-23 (2014). ICC/IF ; Human . PubMed: 24872507
  • Witek ME  et al. A novel CDX2 isoform regulates alternative splicing. PLoS One 9:e104293 (2014). ICC/IF ; Human . PubMed: 25101906
  • Gavrilov AA  et al. Disclosure of a structural milieu for the proximity ligation reveals the elusive nature of an active chromatin hub. Nucleic Acids Res 41:3563-75 (2013). ICC/IF ; Mouse . PubMed: 23396278
  • Mbonye UR  et al. Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes. PLoS Pathog 9:e1003338 (2013). ICC/IF ; Human . PubMed: 23658523
  • Filippello A  et al. Identification of nuclear retention domains in the RBM20 protein. FEBS Lett 587:2989-95 (2013). PubMed: 23886709
  • Karunakaran DK  et al. Expression analysis of an evolutionarily conserved alternative splicing factor, sfrs10, in age-related macular degeneration. PLoS One 8:e75964 (2013). IHC . PubMed: 24098751
  • Morchikh M  et al. TOX4 and NOVA1 Proteins Are Partners of the LEDGF PWWP Domain and Affect HIV-1 Replication. PLoS One 8:e81217 (2013). ICC/IF ; Human . PubMed: 24312278
  • Copeland AM  et al. Nuclear relocalization of polyadenylate binding protein during rift valley fever virus infection involves expression of the NSs gene. J Virol 87:11659-69 (2013). Human . PubMed: 23966414
  • Palmer SJ  et al. GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members. J Cell Sci 125:5040-50 (2012). ICC/IF ; Mouse, Human . PubMed: 22899722
  • Ligasová A  et al. Atomic scissors: a new method of tracking the 5-bromo-2'-deoxyuridine-labeled DNA in situ. PLoS One 7:e52584 (2012). ICC/IF . PubMed: 23300711
  • Park R  et al. Efficient Induction of Nuclear Aggresomes by Specific Single Missense Mutations in the DNA-binding Domain of a Viral AP-1 Homolog. J Biol Chem 286:9748-62 (2011). ICC/IF ; Human . PubMed: 21233201
  • Burgess HM  et al. Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs. J Cell Sci 124:3344-55 (2011). ICC/IF ; Human . PubMed: 21940797
  • Banman SL  et al. Nuclear redistribution of TCERG1 is required for its ability to inhibit the transcriptional and anti-proliferative activities of C/EBPalpha. J Cell Biochem 109:140-51 (2010). ICC/IF ; Human, African green monkey . PubMed: 19911371
  • Ligasová A & Koberna K In situ reverse transcription: the magic of strength and anonymity. Nucleic Acids Res 38:e167 (2010). ICC/IF ; Human . PubMed: 20627869
  • Shan X  et al. Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. Proc Natl Acad Sci U S A 107:16325-30 (2010). IHC-FoFr ; Mouse . PubMed: 20736350
  • Hurt JA  et al. A conserved CCCH-type zinc finger protein regulates mRNA nuclear adenylation and export. J Cell Biol 185:265-77 (2009). ICC/IF ; Human . PubMed: 19364924
  • Bensaid M  et al. FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure. Nucleic Acids Res 37:1269-79 (2009). ICC/IF ; Human . PubMed: 19136466
  • Blanco AM  et al. A FRET-based assay for characterization of alternative splicing events using peptide nucleic acid fluorescence in situ hybridization. Nucleic Acids Res 37:e116 (2009). ICC/IF ; Human . PubMed: 19561195
  • Vos MJ  et al. HSPB7 is a SC35 speckle resident small heat shock protein. Biochim Biophys Acta 1793:1343-53 (2009). PubMed: 19464326
  • Han Z  et al. Intracellular localization of hepatitis delta virus proteins in the presence and absence of viral RNA accumulation. J Virol 83:6457-63 (2009). ICC/IF ; Human . PubMed: 19369324
  • de Chiara C  et al. Phosphorylation of s776 and 14-3-3 binding modulate ataxin-1 interaction with splicing factors. PLoS One 4:e8372 (2009). ICC/IF ; Human . PubMed: 20037628
  • Eisenreich A  et al. Cdc2-like kinases and DNA topoisomerase I regulate alternative splicing of tissue factor in human endothelial cells. Circ Res 104:589-99 (2009). WB ; Human . PubMed: 19168442
  • Bártová E  et al. Single-cell c-myc gene expression in relationship to nuclear domains. Chromosome Res 16:325-43 (2008). ICC/IF ; Human . PubMed: 18320361
  • Chang J  et al. Transcription of hepatitis delta virus RNA by RNA polymerase II. J Virol 82:1118-27 (2008). ICC/IF . PubMed: 18032511
  • Shi J  et al. Caffeine regulates alternative splicing in a subset of cancer-associated genes: a role for SC35. Mol Cell Biol 28:883-95 (2008). PubMed: 18025108
  • Salsman J  et al. Genome-wide screen of three herpesviruses for protein subcellular localization and alteration of PML nuclear bodies. PLoS Pathog 4:e1000100 (2008). ICC/IF ; Human . PubMed: 18617993
  • Maubach G  et al. Nuclear cathepsin F regulates activation markers in rat hepatic stellate cells. Mol Biol Cell 19:4238-48 (2008). ICC/IF ; Rat . PubMed: 18667530
  • Ihalainen TO  et al. Dynamics and interactions of parvoviral NS1 protein in the nucleus. Cell Microbiol 9:1946-59 (2007). PubMed: 17419720
  • Friedman JS  et al. Premature truncation of a novel protein, RD3, exhibiting subnuclear localization is associated with retinal degeneration. Am J Hum Genet 79:1059-70 (2006). PubMed: 17186464
  • Chang J  et al. Development of a novel system to study hepatitis delta virus genome replication. J Virol 79:8182-8 (2005). PubMed: 15956563


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