Anti-Sca1 / Ly6A/E antibody [D7] (PE/Cy5®) (ab24880)

Overview

  • Product nameAnti-Sca1 / Ly6A/E antibody [D7] (PE/Cy5®)
    See all Sca1 / Ly6A/E primary antibodies
  • Description
    Rat monoclonal [D7] to Sca1 / Ly6A/E (PE/Cy5®)
  • ConjugationPE/Cy5®. Ex: 496nm, Em: 670nm
  • SpecificityThis antibody is specific to Ly6A.2 and Ly6E.1, allelic members of the Ly6 multigene family.
  • Tested applicationsSuitable for: Flow Cyt, IP, WB, IHC-Fr, Celluar Activationmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Tissue/ cell preparation: IL2 dependent mouse T cell line CTL-L.

  • General notesThis product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.

Properties

Applications

Our Abpromise guarantee covers the use of ab24880 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.2µg for 106 cells.
IP Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 18 kDa.
IHC-Fr Use at an assay dependent dilution.
Celluar Activation Use at an assay dependent dilution. (In vitro lymphocyte activation.)

Target

  • FunctionT-cell activation.
  • Tissue specificityWidely expressed.
  • Sequence similaritiesContains 1 UPAR/Ly6 domain.
  • Post-translational
    modifications
    O-glycosylated. Not N-glycosylated.
    Not phosphorylated.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ly-6A.2/Ly-6E. antibody
    • Ly-6A.2/Ly-6E.1 antibody
    • Ly6a antibody
    • LY6A_MOUSE antibody
    • Ly6al antibody
    • Lymphocyte antigen 6A-2/6E-1 antibody
    • Lymphocyte antigen Ly 6A.2/Ly 6E.1 antibody
    • SCA-1 antibody
    • Stem cell antigen 1 antibody
    • T cell activating protein antibody
    • T-cell-activating protein antibody
    • TAP antibody
    see all

Anti-Sca1 / Ly6A/E antibody [D7] (PE/Cy5®) images

References for Anti-Sca1 / Ly6A/E antibody [D7] (PE/Cy5®) (ab24880)

This product has been referenced in:
  • Ortega G  et al. Role of Ly-6 in lymphocyte activation. I. Characterization of a monoclonal antibody to a nonpolymorphic Ly-6 specificity. J Immunol 137:3240-6 (1986). Read more (PubMed: 2430016) »

See 1 Publication for this product

Product Wall

Thank you for contacting us. I was checking UniProt and NCBI protein databases for the human sca1 sequence, but was not able to find it. Only the sca2 sequence (http://www.uniprot.org/uniprot/Q16553) was available for human. Maybe sca1 is not pre...

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