Overview

  • Product name
  • Description
    Rabbit polyclonal to SCAI
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 318-367 (PGMQESADKP TRRENPHKYL LYKPTFSQLY TFLAASFKEL PANSVLLIYL) of Human SCAI (NP_775961; UniProt ID: Q8N9R8 isoform 2).

  • Positive control
    • HCT15 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab125375 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 73 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Tumor suppressor which functions to suppress MKL1-induced SRF transcriptional activity. May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1.
  • Sequence similarities
    Belongs to the SCAI family.
  • Cellular localization
    Membrane. Nucleus. Cytoplasm. Nuclear localization is required for inhibition of MKL1.
  • Information by UniProt
  • Database links
  • Alternative names
    • C9orf126 antibody
    • FLJ11758 antibody
    • FLJ36664 antibody
    • MGC120525 antibody
    • MGC120526 antibody
    • MGC120528 antibody
    • NET40 antibody
    • Protein SCAI antibody
    • SCAI antibody
    • SCAI_HUMAN antibody
    • Suppressor of cancer cell invasion antibody
    • Suppressor of cancer cell invasion protein antibody
    see all

Images

  • Anti-SCAI antibody (ab125375) at 1 µg/ml + HCT15 cell lysate at 10 µg

    Predicted band size : 73 kDa

References

ab125375 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab125375.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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