Overview

  • Product nameAnti-SCAMP5 antibody
    See all SCAMP5 primary antibodies
  • Description
    Rabbit polyclonal to SCAMP5
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 163-212 (VFSFIALSMV HKFYRGSGGS FSKAQEEWTT GAWKNPHVQQ AAQNAAMGAA) of Mouse SCAMP5 (NP_064666).

  • Positive control
    • Mouse liver lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab115788 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRequired for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway.
  • Tissue specificityExpressed both by neuronal and nonneuronal tissues. Expressed in brain, stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland, bone marrow and in the different parts of brain. In thyroid tissues, it is expressed by the follicular epithelial cells. In the adrenal gland tissues it is detected in the zona fasciculate of the cortex region (at protein level).
  • Sequence similaritiesBelongs to the SCAMP family. SCAMP5 subfamily.
  • Cellular localizationCell membrane. Golgi apparatus membrane. Golgi apparatus > trans-Golgi network membrane. Recycling endosome membrane. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Mainly localizes in Golgi apparatus membrane. Upon calcium-triggered exocytosis, it translocates to the cell membrane. Highly enriched in synaptic vesicles.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI426171 antibody
    • AW558254 antibody
    • DKFZp686L1799 antibody
    • hSCAMP5 antibody
    • MGC24969 antibody
    • Sc5 antibody
    • SCAM5_HUMAN antibody
    • Scamp5 antibody
    • Secretory carrier associated membrane protein 5 antibody
    • Secretory carrier membrane protein 5 antibody
    • Secretory carrier-associated membrane protein 5 antibody
    see all

Anti-SCAMP5 antibody images

  • Anti-SCAMP5 antibody (ab115788) at 1 µg/ml + Mouse liver lysate at 10 µg

    Predicted band size : 26 kDa

References for Anti-SCAMP5 antibody (ab115788)

ab115788 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"