Overview

  • Product name
  • Description
    Goat polyclonal to SCAP2
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog
  • Immunogen

    Synthetic peptide:

    (C)GLVPKAYIMEMYDI

    , corresponding to C terminal amino acids 346-359 of Human SCAP2

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, 0.5mg/ml Tris, pH 7.3
  • Concentration information loading...
  • Purity
    Ammonium Sulphate Precipitation
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab2484 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    ELISA: 1/32000.
    WB: Use at a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 42.2 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.
    • Tissue specificity
      Ubiquitously expressed. Present in platelets (at protein level).
    • Sequence similarities
      Belongs to the SKAP family.
      Contains 1 PH domain.
      Contains 1 SH3 domain.
    • Domain
      The SH3 domain interacts with FYB and PTK2B.
    • Post-translational
      modifications
      Phosphorylated in resting platelets. Phosphorylated by FYN on Tyr-261 upon T-cell activation (Probable). Dephosphorylated on Tyr-75 by PTPN22.
    • Cellular localization
      Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • Fyn associated phosphoprotein SKAP55 homologue antibody
      • MGC10411 antibody
      • MGC33 antibody
      • PRAP antibody
      • Pyk2/RAFTK associated protein antibody
      • Pyk2/RAFTK-associated protein antibody
      • RA70 antibody
      • Retinoic acid-induced protein 70 antibody
      • SAPS antibody
      • SKAP-55HOM antibody
      • SKAP-HOM antibody
      • skap2 antibody
      • SKAP2_HUMAN antibody
      • SKAP55 homolog antibody
      • SKAP55R antibody
      • Src associated adaptor protein antibody
      • Src family associated phosphoprotein 2 antibody
      • Src family-associated phosphoprotein 2 antibody
      • src kinase associated phosphoprotein of 55 related protein antibody
      • Src kinase-associated phosphoprotein 2 antibody
      • Src kinase-associated phosphoprotein 55-related protein antibody
      • Src-associated adapter protein with PH and SH3 domains antibody
      see all

    Anti-SCAP2 antibody images

    • Anti-SCAP2 antibody (ab2484) at 0.5 µg/ml + Jurkat lysate at 35 µg

      Predicted band size : 42.2 kDa

    References for Anti-SCAP2 antibody (ab2484)

    This product has been referenced in:
    • Haanstra KG  et al. Expression patterns of regulatory T-cell markers in accepted and rejected nonhuman primate kidney allografts. Am J Transplant 7:2236-46 (2007). Read more (PubMed: 17845559) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab2484.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up