Overview

  • Product nameAnti-SCARA5 antibody
    See all SCARA5 primary antibodies
  • Description
    Rabbit polyclonal to SCARA5
  • Tested applicationsSuitable for: ELISA, ICC, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    17 amino acid synthetic peptide near the carboxy terminus of Human SCARA5.

  • Positive control
    • Human Small Intestine tissue; Human liver tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab118894 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
ICC Use at an assay dependent concentration.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 54 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • FunctionFerritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).
  • Sequence similaritiesBelongs to the SCARA5 family.
    Contains 1 collagen-like domain.
    Contains 1 SRCR domain.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • FormThere are 4 isoforms produced by alternative splicing.
  • Alternative names
    • FLJ23907 antibody
    • MGC45780 antibody
    • NET33 antibody
    • SCAR5_HUMAN antibody
    • SCARA 5 antibody
    • scara5 antibody
    • Scavenger receptor class A member 5 antibody
    • Scavenger receptor class A, member 5 (putative) antibody
    • Scavenger receptor class A, member 5 antibody
    • Scavenger receptor hlg antibody
    • Tesr antibody
    • Testis expressed scavenger receptor antibody
    see all

Anti-SCARA5 antibody images

  • Anti-SCARA5 antibody (ab118894) at 1 µg/ml + Human liver tissue lysate

    Predicted band size : 54 kDa
  • ab118894t 5µg/ml, staining SCARA5 in Formalin-fixed, Paraffin-embedded Human Small intestine tissue by Immunohistochemistry.

References for Anti-SCARA5 antibody (ab118894)

This product has been referenced in:
  • Liu J  et al. Suppression of SCARA5 by Snail1 is essential for EMT-associated cell migration of A549 cells. Oncogenesis 2:e73 (2013). WB . Read more (PubMed: 24061576) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"