Overview

  • Product name
  • Description
    Goat polyclonal to SCARF1
  • Specificity
    This antibody is expected to recognise all 5 isoforms of SCARF1.
  • Tested applications
    Suitable for: ELISA, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    SELDPKGQHVC

    , corresponding to amino acids 20 - 31 of Human SCARF1.

  • Positive control
    • Human heart lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab23933 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/32000.
ICC/IF Use at an assay dependent dilution. PubMed: 20606164
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 85-90 kDa (predicted molecular weight: 87 kDa).

Target

  • Function
    Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth.
  • Tissue specificity
    Endothelial cells.
  • Sequence similarities
    Contains 6 EGF-like domains.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Acetyl LDL receptor antibody
    • Endothelial cells scavenger receptor antibody
    • SCARF1 antibody
    • Scavenger receptor class F member 1 antibody
    • Scavenger receptor expressed by endothelial cells 1 antibody
    • Scavenger receptor expressed by endothelial cells antibody
    • SREC antibody
    • SREC-I antibody
    • SREC_HUMAN antibody
    see all

Images

  • All lanes : Anti-SCARF1 antibody (ab23933) at 0.3 µg/ml

    Lane 1 : (A) Human Heart lysate
    Lane 2 : (B) Human Heart lysate with immunizing peptide

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 87 kDa
    Observed band size : 85-90 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 28 kDa (possible non-specific binding).

References

This product has been referenced in:
  • Narazaki M  et al. Oligo-guanosinenucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis. Blood : (2010). ICC/IF ; Human . Read more (PubMed: 20606164) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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