Anti-Scavenging Receptor SR-BI antibody (ab125433)

Overview

  • Product nameAnti-Scavenging Receptor SR-BI antibody
    See all Scavenging Receptor SR-BI primary antibodies
  • Description
    Rabbit polyclonal to Scavenging Receptor SR-BI
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rabbit, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 114-163 (LEYRTFQFQP SKSHGSESDY IVMPNILVLG AAVMMENKPM TLKLIMTLAF) of Human Scavenging Receptor SR-BI (NP_001076428; UniProt ID: F8W8N0).

  • Positive control
    • Human fetal kidney lysate.

Applications

Our Abpromise guarantee covers the use of ab125433 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionReceptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester.
  • Tissue specificityWidely expressed.
  • Sequence similaritiesBelongs to the CD36 family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationCell membrane. Membrane > caveola. Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD36 and LIMPII analogous 1 antibody
    • CD36 antibody
    • CD36 Antigen like 1 antibody
    • CD36 antigen-like 1 antibody
    • CD36L1 antibody
    • CLA 1 antibody
    • CLA-1 antibody
    • CLA1 antibody
    • Collagen type I receptor antibody
    • HDLQTL6 antibody
    • MGC138242 antibody
    • SCARB1 antibody
    • Scavebger Receptor Class B Member 1 antibody
    • Scavenger receptor class B member 1 antibody
    • Scavenger Receptor Class B Type 1 antibody
    • SCRB1_HUMAN antibody
    • SR BI antibody
    • SR-BI antibody
    • SRB1 antibody
    • SRBI antibody
    • Thrombospondin receptor like 1 antibody
    • thrombospondin receptor-like 1 antibody
    see all

Anti-Scavenging Receptor SR-BI antibody images

  • Anti-Scavenging Receptor SR-BI antibody (ab125433) at 1 µg/ml + Human fetal kidney lysate at 10 µg

    Predicted band size : 56 kDa

References for Anti-Scavenging Receptor SR-BI antibody (ab125433)

ab125433 has not yet been referenced specifically in any publications.

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