Anti-SCC112 antibody (ab17961)
Key features and details
- Rabbit polyclonal to SCC112
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-SCC112 antibody
See all SCC112 primary antibodies -
Description
Rabbit polyclonal to SCC112 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan -
Immunogen
Synthetic peptide within Human SCC112 aa 1250-1350 (C terminal). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q29RF7 -
Positive control
- WB: HeLa and HEK-293T whole cell lysates.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7
Preservative: 0.1% Sodium azide
Constituents: 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab17961 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/10000 - 1/25000. Detects a band of approximately 145 kDa (predicted molecular weight: 150 kDa).
|
Notes |
---|
WB
1/10000 - 1/25000. Detects a band of approximately 145 kDa (predicted molecular weight: 150 kDa). |
Target
-
Function
Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. -
Tissue specificity
Highest level in colon. Low levels in lung, ovary, breast and kidney. Reduced level in renal tumor tissue. Isoform 2 is expressed in kidney. -
Sequence similarities
Belongs to the PDS5 family.
Contains 1 HEAT repeat. -
Developmental stage
Cell cycle-regulated with highest level in G2 phase. -
Cellular localization
Nucleus. Associated with chromatin through most of the cell cycle. Dissociates from chromatin in late prophase, reassociates during late telophase. - Information by UniProt
-
Database links
- Entrez Gene: 23244 Human
- Omim: 613200 Human
- SwissProt: Q29RF7 Human
- Unigene: 331431 Human
-
Alternative names
- Cell proliferation inducing protein 54 antibody
- Cell proliferation-inducing gene 54 protein antibody
- KIAA0648 antibody
see all
Images
-
All lanes : Anti-SCC112 antibody (ab17961) at 0.04 µg/ml
Lane 1 : HeLa (Human cervix adenocarcinoma epithelial cell) whole cell lysate
Lane 2 : HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
Lysates/proteins at 50 µg per lane.
Predicted band size: 150 kDa
Exposure time: 30 seconds
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab17961 has not yet been referenced specifically in any publications.