Overview

  • Product name
  • Description
    Goat polyclonal to SCD1
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Pig
  • Immunogen

    Synthetic peptide:

    RIKRTGDGNYKSG

    , corresponding to C terminal amino acids 347-359 of Human SCD (O00767).

  • Positive control
    • Human Colon and Liver tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab111301 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/64000.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function
    Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.
  • Sequence similarities
    Belongs to the fatty acid desaturase family.
  • Domain
    The histidine box domains may contain the active site and/or be involved in metal ion binding.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACOD_HUMAN antibody
    • Acyl-CoA desaturase antibody
    • Delta(9)-desaturase antibody
    • Delta-9 desaturase antibody
    • Delta-9-Desaturase antibody
    • FADS5 antibody
    • Fatty acid desaturase antibody
    • PRO0998 antibody
    • SCD 1 antibody
    • SCD antibody
    • SCD1 antibody
    • Stearoyl-CoA desaturase antibody
    see all

Images

  • Immunohistochemistry Image of Human Colon tissue: Formalin Fixed, Paraffin Embedded (FFPE) and stained with ab111301 at 5µg/ml.
  • Immunohistochemistry Image of Human Liver tissue: Formalin Fixed, Paraffin Embedded (FFPE) and stained with ab111301 at 5µg/ml.

References

This product has been referenced in:
  • Meller S  et al. Integration of tissue metabolomics, transcriptomics and immunohistochemistry reveals ERG- and gleason score-specific metabolomic alterations in prostate cancer. Oncotarget 7:1421-38 (2016). IHC-P ; Human . Read more (PubMed: 26623558) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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