Overview

  • Product nameAnti-SCGN antibody
    See all SCGN primary antibodies
  • Description
    Rabbit polyclonal to SCGN
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 57-238 of Human SCGN (AAH00336).

  • Positive control
    • HeLa and HCT116 cells and whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab111871 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 32 kDa.
ICC/IF 1/100 - 1/500.

Target

  • Tissue specificityExpressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons.
  • Sequence similaritiesContains 6 EF-hand domains.
  • Cellular localizationCytoplasm. Secreted. Cytoplasmic vesicle > secretory vesicle membrane. Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions (By similarity). Detectable in human serum after ischemic neuronal damage.
  • Information by UniProt
  • Database links
  • Alternative names
    • Calbindin like antibody
    • CALBL antibody
    • DJ501N12.8 antibody
    • OTTHUMP00000016124 antibody
    • Scgn antibody
    • SECRET antibody
    • Secretagogin antibody
    • Secretagogin EF hand calcium binding protein antibody
    • SEGN antibody
    • SEGN_HUMAN antibody
    • Setagin antibody
    see all

Anti-SCGN antibody images

  • Anti-SCGN antibody (ab111871) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size : 32 kDa
  • ab111871 at 1/200 dilution staining SCGN in methanol-fixed HeLa cells by Immunofluorescence. The lower image is costained with Hoechst 33342.

References for Anti-SCGN antibody (ab111871)

ab111871 has not yet been referenced specifically in any publications.

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