SCH79797 dihydrochloride (ab120858)

Overview

  • Product nameSCH79797 dihydrochloride
  • Description
    Potent and selective PAR1 antagonist
  • Biological descriptionPotent and selective non-peptide Proteinase-Activated Receptor-1 (PAR1) antagonist (IC50 = 70 nM). Protects against ischemic injury. Additionally induces apoptosis and inhibits cell proliferation.
  • Purity> 98%

Properties

    References for SCH79797 dihydrochloride (ab120858)

    This product has been referenced in:
    • El Eter E & Aldrees A Inhibition of Pro-inflammatory Cytokines by SCH79797, a Selective PAR1 Antagonist, Protects Rat Kidney Against Ischemia Reperfusion Injury. Shock : (2012). Read more (PubMed: 22395241) »
    • Fujimoto D  et al. The activation of Proteinase-Activated Receptor-1 (PAR1) mediates gastric cancer cell proliferation and invasion. BMC Cancer 10:443 (2010). Read more (PubMed: 20723226) »
    • Strande JL  et al. SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts. Basic Res Cardiol 102:350-8 (2007). Read more (PubMed: 17468933) »

    See 0 Publications for this product

    Product Wall

    We would recommend using a lower % final working concentration of DMSO. For instance, the following paper is an example about using DMSO at a final working conc of 0.1%:

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448915/pdf/bph0167-0080.pdf...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"