Overview

  • Product nameAnti-Scn2b antibody
    See all Scn2b primary antibodies
  • Description
    Rabbit polyclonal to Scn2b
  • Tested applicationsSuitable for: WB, Indirect ELISAmore details
  • Species reactivity
    Reacts with: Rat, Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide corresponding to N-terminal residues of Rat Scn2b

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferPreservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab56205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 24 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
Indirect ELISA Use at an assay dependent dilution.

Target

  • FunctionCrucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier.
  • Tissue specificityBrain specific.
  • Sequence similaritiesBelongs to the sodium channel auxiliary subunit SCN2B (TC 8.A.17) family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Neuronal voltage gated sodium channel beta 2 subunit antibody
    • Scn 2b antibody
    • Scn2b antibody
    • SCN2B_HUMAN antibody
    • Sodium channel beta 2 subunit antibody
    • Sodium channel subunit beta 2 antibody
    • Sodium channel subunit beta-2 antibody
    • Sodium channel voltage gated type II beta antibody
    • Sodium channel voltage gated type II beta polypeptide antibody
    see all

Anti-Scn2b antibody images

  • All lanes : Anti-Scn2b antibody (ab56205) at 1 µg/ml

    Lane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate
    Lane 2 : Caco 2 (Human colonic carcinoma cell line) Whole Cell Lysate
    Lane 3 : SW480 (Human colon adenocarcinoma cell line) Whole Cell Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP)

    Predicted band size : 24 kDa
    Observed band size : 24 kDa
    Additional bands at : 30 kDa (possible post-translational modification).

References for Anti-Scn2b antibody (ab56205)

ab56205 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab56205.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"