Overview

  • Product name
  • Description
    Rabbit polyclonal to Scn2b
  • Tested applications
    Suitable for: WB, Indirect ELISAmore details
  • Species reactivity
    Reacts with: Rat, Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide corresponding to N-terminal residues of Rat Scn2b

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    Preservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab56205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 24 kDa.

This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.

Indirect ELISA Use at an assay dependent concentration.

Target

  • Function
    Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier.
  • Tissue specificity
    Brain specific.
  • Sequence similarities
    Belongs to the sodium channel auxiliary subunit SCN2B (TC 8.A.17) family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Neuronal voltage gated sodium channel beta 2 subunit antibody
    • Scn 2b antibody
    • Scn2b antibody
    • SCN2B_HUMAN antibody
    • Sodium channel beta 2 subunit antibody
    • Sodium channel subunit beta 2 antibody
    • Sodium channel subunit beta-2 antibody
    • Sodium channel voltage gated type II beta antibody
    • Sodium channel voltage gated type II beta polypeptide antibody
    see all

References

ab56205 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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