Anti-Scramblase 1 antibody [13A6 [TEC-23]] (ab77122)


  • Product nameAnti-Scramblase 1 antibody [13A6 [TEC-23]]
    See all Scramblase 1 primary antibodies
  • Description
    Mouse monoclonal [13A6 [TEC-23]] to Scramblase 1
  • Tested applicationsSuitable for: WB, IP, Flow Cyt, ICC/IFmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Pooled lipid rafts isolated from RBL-2H3 cells.

  • Positive control
    • Rat basophilic leukemia (RBL) cells and cell lysate. RBL lysate.



Our Abpromise guarantee covers the use of ab77122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa).
IP Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab170191-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
ICC/IF Use at an assay dependent concentration.


  • FunctionMay mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
    May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. May contribute to cytokine-regulated cell proliferation and differentiation.
  • Tissue specificityExpressed in platelets, erythrocyte membranes, lymphocytes, spleen, thymus, prostate, testis, uterus, intestine, colon, heart, placenta, lung, liver, kidney and pancreas. Not detected in brain and skeletal muscle.
  • Sequence similaritiesBelongs to the phospholipid scramblase family.
  • Post-translational
    Known to be palmitoylated at one, yet undefined, site.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ca(2+) dependent phospholipid scramblase 1 antibody
    • Ca(2+)-dependent phospholipid scramblase 1 antibody
    • Erythrocyte phospholipid scramblase antibody
    • MM1 cell-derived transplantability-associated gene 1b, mouse, homolog of antibody
    • MmTRA1a antibody
    • MmTRA1b antibody
    • Nor1 antibody
    • Phospholipid scramblase 1 antibody
    • PL scramblase 1 antibody
    • PLS1_HUMAN antibody
    • PLSCR 1 antibody
    • Plscr1 antibody
    • Scramblase1 antibody
    • Tra1 antibody
    • Tra1a antibody
    • Tra1b antibody
    • Transplantability-associated protein 1 antibody
    • Tras1 antibody
    • Tras2 antibody
    see all

Anti-Scramblase 1 antibody [13A6 [TEC-23]] images

  • ab77122 staining Scramblase 1 in rat basophilic leukemia (RBL) cell line by Immunofluorescence.
  • All lanes : Anti-Scramblase 1 antibody [13A6 [TEC-23]] (ab77122)

    Lane 1 : Rat basophilic leukemia (RBL) cell line lysate
    Lane 2 : Scramblase 1 immunoprecipitate from RBL lysate

    Predicted band size : 35 kDa
    Observed band size : 35 kDa
    Additional bands at : 25 kDa. We are unsure as to the identity of these extra bands.

References for Anti-Scramblase 1 antibody [13A6 [TEC-23]] (ab77122)

This product has been referenced in:
  • Smrz D  et al. Engagement of phospholipid scramblase 1 in activated cells: implication for phosphatidylserine externalization and exocytosis. J Biol Chem 283:10904-18 (2008). Read more (PubMed: 18281686) »

See 1 Publication for this product

Product Wall

The recommended working concentration of 1 ug/ml on the WB image was for an old purified batch of Anti-Scramblase 1 antibody [13A6 [TEC-23]]. However, our current batches are in ascites format (concentration not determined), as purification of this par...

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