Overview

  • Product nameAnti-SCUBE1 antibody
    See all SCUBE1 primary antibodies
  • Description
    Rabbit polyclonal to SCUBE1
  • Specificityab105358 is predicted to not crossreact with other SCUBE members.
  • Tested applicationsSuitable for: ICC/IF, WB, ICCmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A 14 amino acid peptide near the center of Human SCUBE1 (NP_766638).

  • Positive control
    • WB: Daudi cell lysate ICC: Daudi cells

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab105358 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 108 kDa.
ICC Use a concentration of 20 µg/ml.

Target

  • FunctionCould function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
  • Tissue specificityDetected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferrred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques.
  • Sequence similaritiesContains 1 CUB domain.
    Contains 9 EGF-like domains.
  • Post-translational
    modifications
    N-glycosylated.
    Could be proteolytically cleaved to release a smaller active fragment.
  • Cellular localizationSecreted. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • SCUB1_HUMAN antibody
    • SCUBE 1 antibody
    • SCUBE1 antibody
    • Signal peptide, CUB and EGF-like domain-containing protein 1 antibody
    • Signal peptide, CUB domain, EGF like 1 antibody
    see all

Anti-SCUBE1 antibody images

  • Anti-SCUBE1 antibody (ab105358) at 1 µg/ml + Daudi cell lysate at 15 µg

    Predicted band size : 108 kDa
  • Immunocytochemical analysis of SCUBE1 in Daudi cells using ab105358 at 20 µg/ml.
  • Immunofluorescence of SCUBE1 in Daudi cells using ab105358 at 20 ug/ml.

References for Anti-SCUBE1 antibody (ab105358)

ab105358 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab105358.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"