Overview

  • Product name
    Anti-SCYL1BP1 antibody
  • Description
    Rabbit polyclonal to SCYL1BP1
  • Tested applications
    Suitable for: ICC/IF, ChIP, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic peptide corresponding to a sequence at the middle region of human SCYL1BP1, identical to the related rat and mouse sequence.

Properties

  • Form
    Lyophilised:0.2ml of distilled water will yield a concentration of 500µg/ml.
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
    Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab68452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 23051735
ChIP Use at an assay dependent concentration. PubMed: 23051735
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 45 kDa.
IHC-P Use a concentration of 1 - 2 µg/ml.

Target

  • Involvement in disease
    Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.
  • Sequence similarities
    Belongs to the GORAB family.
  • Cellular localization
    Cytoplasm. Golgi apparatus.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ11752 antibody
    • GO antibody
    • Golgin RAB6 interacting antibody
    • GORAB antibody
    • GORAB_HUMAN antibody
    • hNTKL BP1 antibody
    • hNTKL-BP1 antibody
    • MGC51263 antibody
    • MGC70512 antibody
    • N terminal kinase like binding protein 1 antibody
    • N-terminal kinase-like-binding protein 1 antibody
    • NTKL binding protein 1 antibody
    • NTKL BP1 antibody
    • NTKL-binding protein 1 antibody
    • NTKL-BP1 antibody
    • NTKLBP 1 antibody
    • NTKLBP1 antibody
    • OTTHUMP00000033164 antibody
    • RAB6-interacting golgin antibody
    • RP11 545I10.1 antibody
    • SCY1 like 1 binding protein 1 antibody
    • SCY1-like 1-binding protein 1 antibody
    • SCYL1 binding protein 1 antibody
    • SCYL1 BP1 antibody
    • SCYL1-binding protein 1 antibody
    • SCYL1-BP1 antibody
    • SCYL1BP1 antibody
    see all

Images

  • ab68452 at 1µg/ml staining SCYL1BP1 in Human ambulant adenocarcinoma tissue sections by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded tissue sections). The tissue sections underwent antigen retrieval by boiling. A Biotin-conjugated Goat anti-rabbit IgG was used as secondary at 1/200 dilution.

References

This product has been referenced in:
  • Liu Y  et al. SCYL1BP1 modulates neurite outgrowth and regeneration by regulating the Mdm2/p53 pathway. Mol Biol Cell 23:4506-14 (2012). WB, ICC/IF, ChIP ; Rat . Read more (PubMed: 23051735) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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