Overview

  • Product name
    SD 169
  • Description
    Potent, selective and ATP-competitive p38α MAPK inhibitor
  • Biological description
    Potent, selective and ATP-competitive p38α MAPK inhibitor (IC50 values are 3.2 and 122 nM for α and β, respectively). Orally active. Promotes axonal regeneration in vivo.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Medicherla S  et al. Preventive and therapeutic potential of p38 alpha-selective mitogen-activated protein kinase inhibitor in nonobese diabetic mice with type 1 diabetes. J Pharmacol Exp Ther 318:99-107 (2006). Read more (PubMed: 16603672) »
  • Myers RR  et al. Inhibition of p38 MAP kinase activity enhances axonal regeneration. Exp Neurol 184:606-14 (2003). Read more (PubMed: 14769353) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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