Overview

  • Product name
  • Description
    Rabbit polyclonal to SDCCAG8
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within the N terminal amino acids 107-156 (HEETNMPTMH DLVHTINDQS QYIHHLEAEV KFCKEELSGM KNKIQVVVLE) of Human SDCCAG8 (NP_006633).

  • Positive control
    • THP-1 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab101969 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 83 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis.
  • Tissue specificity
    Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.
  • Involvement in disease
    Senior-Loken syndrome 7 (SLSN7) [MIM:613615]: A renal-retinal disorder characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes apparent during the first year of life. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Cellular localization
    Cytoplasm and Cytoplasm > cytoskeleton > centrosome > centriole. Cell junction. Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antigen NY CO 8 antibody
    • Antigen NY-CO-8 antibody
    • BBS16 antibody
    • CCCAP antibody
    • CCCAP SLSN7 antibody
    • Centrosomal colon cancer autoantigen protein antibody
    • hCCCAP antibody
    • HSPC085 antibody
    • NPHP10 antibody
    • NPHP10 gene antibody
    • NY-CO-8 antibody
    • Sdccag8 antibody
    • SDCG8_HUMAN antibody
    • Serologically defined colon cancer antigen 8 antibody
    • Serologically defined colon cancer antigen 8 homolog antibody
    • SLSN7 antibody
    • SLSN7 gene antibody
    see all

Images

  • Anti-SDCCAG8 antibody (ab101969) at 1 µg/ml + THP-1 cell lysate at 10 µg

    Predicted band size : 83 kDa

References

This product has been referenced in:
  • Airik R  et al. Renal-Retinal Ciliopathy Gene Sdccag8 Regulates DNA Damage Response Signaling. J Am Soc Nephrol N/A:N/A (2014). Human . Read more (PubMed: 24722439) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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