Overview

  • Product name
  • Description
    Rabbit polyclonal to SDPR
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Hamster, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 115-145 of Human SDPR.

  • Positive control
    • CHO cell line lysates; Human lung carcinoma tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Ammonium Sulphate Precipitation
  • Purification notes
    ab103230 is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab103230 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 47 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May play a role in targeting PRKCA to caveolae.
  • Tissue specificity
    Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle.
  • Sequence similarities
    Belongs to the PTRF/SDPR family.
  • Post-translational
    modifications
    Phosphorylated on Ser residues.
  • Cellular localization
    Cytoplasm > cytosol. Membrane > caveola. Colocalizes with CAV1 to caveolae.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cavin 2 antibody
    • Cavin-2 antibody
    • Phosphatidylserine binding protein antibody
    • Phosphatidylserine-binding protein antibody
    • PS p68 antibody
    • PS-p68 antibody
    • Sdpr antibody
    • SDPR_HUMAN antibody
    • SDR antibody
    • Serum deprivation response antibody
    • Serum deprivation response protein antibody
    • Serum deprivation-response protein antibody
    see all

Images

  • Anti-SDPR antibody (ab103230) at 1/100 dilution + CHO cell line lysates at 35 µg

    Predicted band size : 47 kDa
  • ab103230 at 1/50 dilution, staining SDPR in Human lung carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining.

References

This product has been referenced in:
  • Tian Y  et al. Serum deprivation response inhibits breast cancer progression by blocking transforming growth factor-ß signaling. Cancer Sci 107:274-80 (2016). Read more (PubMed: 26749136) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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