Overview

  • Product name
  • Description
    Rabbit polyclonal to SDPR
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Goat, Horse, Guinea pig, Cow, Cat, Human, Pig
  • Immunogen

    Synthetic peptide from a region within N terminal amino acids 80-129: EQRQINLEGS VKGIQNDLTK LSKYQASTSN TVSKLLEKSR KVSAHTRAVR, of Mouse SDPR (NP_620080).

  • Positive control
    • Mouse heart lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Constituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab113876 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 47 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    May play a role in targeting PRKCA to caveolae.
  • Tissue specificity
    Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle.
  • Sequence similarities
    Belongs to the PTRF/SDPR family.
  • Post-translational
    modifications
    Phosphorylated on Ser residues.
  • Cellular localization
    Cytoplasm > cytosol. Membrane > caveola. Colocalizes with CAV1 to caveolae.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cavin 2 antibody
    • Cavin-2 antibody
    • Phosphatidylserine binding protein antibody
    • Phosphatidylserine-binding protein antibody
    • PS p68 antibody
    • PS-p68 antibody
    • Sdpr antibody
    • SDPR_HUMAN antibody
    • SDR antibody
    • Serum deprivation response antibody
    • Serum deprivation response protein antibody
    • Serum deprivation-response protein antibody
    see all

Images

  • Anti-SDPR antibody (ab113876) at 1 µg/ml + Mouse heart lysate at 10 µg

    Predicted band size : 47 kDa

References

This product has been referenced in:
  • Zhu B  et al. Similar regulatory mechanisms of caveolins and cavins by myocardin family coactivators in arterial and bladder smooth muscle. PLoS One 12:e0176759 (2017). WB . Read more (PubMed: 28542204) »
  • Krawczyk KK  et al. Myocardin Family Members Drive Formation of Caveolae. PLoS One 10:e0133931 (2015). WB . Read more (PubMed: 26244347) »

See all 4 Publications for this product

Customer reviews and Q&As

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunocytochemistry/ Immunofluorescence
Sample
Rat Cell (cardiac myocytes)
Permeabilization
Yes - 0.01% Triton
Specification
cardiac myocytes
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: RT°C
Fixative
Formaldehyde
Username

Ruth Norman

Verified customer

Submitted Feb 20 2017

Application
Immunocytochemistry/ Immunofluorescence
Sample
Mouse Cell (bEnd.3)
Permeabilization
Yes - 0.1% triton in PBS
Specification
bEnd.3
Blocking step
Serum as blocking agent for 30 minute(s) · Concentration: 10% · Temperature: 22°C
Fixative
Paraformaldehyde
Username

Abcam user community

Verified customer

Submitted Nov 19 2015

Application
Western blot
Sample
Human Tissue lysate - whole (liver,colon,lung,breast, prostate)
Gel Running Conditions
Reduced Denaturing (10% seperation gel)
Loading amount
35 µg
Specification
liver,colon,lung,breast, prostate
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 37°C
Username

Kailun Lyu

Verified customer

Submitted Oct 19 2015

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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