Anti-SDS3 antibody (ab3740)

Overview

• Product nameAnti-SDS3 antibody
  See all SDS3 primary antibodies
• Description
  Goat polyclonal to SDS3
• Tested applicationsSuitable for: WB, IPmore details
• Species reactivity
  Reacts with: Mouse, Human
  Predicted to work with: Rabbit, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Zebrafish, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
• Immunogen

  Synthetic peptide (Human) - which represented a portion of human Suppressor of Defective Silencing 3 encoded in part by exons 7 and 8.

• Positive control
  • HeLa cell lysate.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: 0.1% Sodium Azide
  Constituents: 8mM PBS, 60mM Citrate, 150mM Tris, pH 7-8
• Concentration information loading...
• PurityImmunogen affinity purified
• ClonalityPolyclonal
• IsotypeIgG
• Research areas
  • Epigenetics and Nuclear Signaling
  • Transcription
  • Cancer susceptibility
  • Tumor Suppressors

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Other factors

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Co-factors

  • Epigenetics and Nuclear Signaling
  • Chromatin Modifying Enzymes
  • Acetylation
  • HAT

Applications

Target

• FunctionRegulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways (By similarity). May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
• Tissue specificityExpressed in various cancer cell ines.
• Sequence similaritiesBelongs to the SDS3 family.
• DomainThe C-terminus is involved in transcriptional repression by HDAC-independent mechanisms.

• Target information above from: UniProt accession Q9H7L9 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 64426 Human
  • Entrez Gene: 71954 Mouse
  • Entrez Gene: 445099 Zebrafish
  • Omim: 608250 Human
  • SwissProt: Q9H7L9 Human
  • SwissProt: Q8BR65 Mouse
  • SwissProt: Q803C3 Zebrafish
  • Unigene: 416630 Human

  • Unigene: 602312 Human
  • Unigene: 34456 Mouse

  see all
• Alternative names
  • 2400003N08Rik antibody
  • 2410008L21Rik antibody
  • 45 kDa Sin3 associated polypeptide antibody

  • 45 kDa Sin3-associated polypeptide antibody
  • AU067672 antibody
  • FLJ00052 antibody
  • MGC104711 antibody
  • mSds3 antibody
  • RGD1305986 antibody
  • SAP45 antibody
  • SDS3 antibody
  • SDS3, yeast, homolog of antibody
  • SDS3_HUMAN antibody
  • Sin3 histone deacetylase corepressor complex component SDS3 antibody
  • Sin3A associated protein 45kDa antibody
  • Suds3 antibody
  • Suppressor of defective silencing 3 antibody
  • Suppressor of defective silencing 3 homolog (S cerevisiae) antibody
  • Suppressor of defective silencing 3 homolog (SDS3 S cerevisiae) antibody
  • Suppressor of defective silencing 3 protein homolog antibody

  see all